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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
PPM1D Protein (AA 496-605) (GST tag) PPM1D Protein (AA 496-605) (GST tag) PPM1D Protein (AA 496-605) (GST tag) (ABIN1315910)

PPM1D 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

PPM1D Protein (AA 1-605) (GST tag) PPM1D Protein (AA 1-605) (GST tag) PPM1D Protein (AA 1-605) (GST tag) (ABIN1315909)

PPM1D 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

PPM1D Protein (AA 98-375) (His tag) (ABIN5623952)

PPM1D 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % pure SDS

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白 by Origin

Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白 for a variety of species such as anti-Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D, anti-Mouse Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D. The species listed below are among those available. Click on a link to go to the corresponding products.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白 by Source

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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白 by 蛋白类型

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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白 by 应用范围

Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白 validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315909
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623952
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086448
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130585
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729806
Quantity 20 μg
Datasheet Datasheet

Aliases for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 蛋白

protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) 蛋白
protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent, 1Db (ppm1db) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) 蛋白
protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) 蛋白
AV338790 蛋白
PP2C-DELTA 蛋白
ppm1d 蛋白
WIP1 蛋白
Wip1 蛋白
wu:fj44c08 蛋白
zgc:55836 蛋白
zgc:77316 蛋白
zgc:103518 蛋白
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