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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D ELISA试剂盒

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
PPM1D ELISA 试剂盒 PPM1D ELISA 试剂盒 PPM1D ELISA 试剂盒 (ABIN6958950)

PPM1D 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate

PPM1D ELISA 试剂盒 (ABIN422939)

PPM1D 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum

PPM1D ELISA 试剂盒 (ABIN6232982)

PPM1D 适用: 人 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate

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Popular Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958950
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN422939
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6232982
Quantity 96 tests
Datasheet Datasheet

Aliases for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D ELISA试剂盒

protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) ELISA试剂盒
protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) ELISA试剂盒
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) ELISA试剂盒
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