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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D ELISA试剂盒

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
PPM1D ELISA 试剂盒 PPM1D ELISA 试剂盒 PPM1D ELISA 试剂盒 (ABIN6958950)

PPM1D 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate

PPM1D ELISA 试剂盒 (ABIN422939)

PPM1D 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Plasma, Serum

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Popular Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958950
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN422939
Quantity 96 tests
Datasheet Datasheet

Aliases for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D ELISA试剂盒

protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) ELISA试剂盒
protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) ELISA试剂盒
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) ELISA试剂盒
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