Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体
(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development. [provided by RefSeq, Jul 2008].
recommended
PPM1D 适用: 人 WB, ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
recommended
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 by 适用
Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 for a variety of species such as anti-Human Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D, anti-Mouse Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D, anti-Rat Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D. The species listed below are among those available. Click on a link to go to the corresponding products.
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 by 应用范围
Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 validated for a specific application such as WB, ELISA, IF (cc), IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 by 抗体来源
Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 by 抗原表位
Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 by 克隆形成能力
Find available monoclonal or polyclonal Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体. Click on a link to go to the corresponding products.
Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 by 克隆
Find Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN740415
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7165942
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN563650
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6972548
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), ICC
Validations
- (1)
Cat. No.
ABIN7506006
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (8)
- (1)
Cat. No.
ABIN392853
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN657796
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC (p)
Validations
Cat. No.
ABIN6989347
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
Cat. No.
ABIN740417
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC (p)
Validations
Cat. No.
ABIN6982935
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc)
Validations
Cat. No.
ABIN919985
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc)
Validations
Cat. No.
ABIN2805513
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc)
Validations
Cat. No.
ABIN5009099
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc)
Validations
Cat. No.
ABIN5009100
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (cc)
Validations
Cat. No.
ABIN919982
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体
: "Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway." in: Oncology letters, Vol. 12, Issue 6, pp. 4605-4612, (2017) (PubMed).: "p53-Independent expression of wild-type p53-induced phosphatase 1 (Wip1) in methylmethane sulfonate-treated cancer cell lines and human tumors." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 6, pp. 896-904, (2012) (PubMed).
: "HDM2 promotes WIP1-mediated medulloblastoma growth." in: Neuro-oncology, Vol. 14, Issue 4, pp. 440-58, (2012) (PubMed).
: "p16Ink4a suppression of lung adenocarcinoma by Bmi-1 in the presence of p38 activation." in: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, Vol. 6, Issue 3, pp. 423-31, (2011) (PubMed).
: "Expression of a homeostatic regulator, Wip1 (wild-type p53-induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9067-76, (2010) (PubMed).
: "Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 12935-47, (2010) (PubMed).
: "Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway." in: Cancer research, Vol. 70, Issue 18, pp. 7176-86, (2010) (PubMed).
: "The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair." in: DNA repair, Vol. 9, Issue 7, pp. 813-23, (2010) (PubMed).
: "Nuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase." in: The Journal of biological chemistry, Vol. 285, Issue 8, pp. 5249-57, (2010) (PubMed).
: "BRCA1-IRIS overexpression abrogates UV-induced p38MAPK/p53 and promotes proliferation of damaged cells." in: Oncogene, Vol. 29, Issue 38, pp. 5274-85, (2010) (PubMed).
Aliases for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D 抗体
protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) 抗体protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) 抗体
protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) 抗体
protein phosphatase, Mg2+/Mn2+ dependent, 1Db (ppm1db) 抗体
protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) 抗体
protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) 抗体
AV338790 抗体
PP2C-DELTA 抗体
ppm1d 抗体
WIP1 抗体
Wip1 抗体
wu:fj44c08 抗体
zgc:55836 抗体
zgc:77316 抗体
zgc:103518 抗体
您还需要查找其他产品吗？
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B 抗体
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A 抗体
- Protein Phosphatase 4, Regulatory Subunit 2 抗体
- Protein Phosphatase 2, Regulatory Subunit B', epsilon Isoform 抗体
- Protein Phosphatase 2, Regulatory Subunit B', delta 抗体
- Protein Phosphatase 2, Regulatory Subunit B' alpha 抗体
- Protein Phosphatase 1, Regulatory Subunit 3C 抗体
- Protein Phosphatase 1, Regulatory Subunit 3B 抗体
- Protein Phosphatase 1, Catalytic Subunit, alpha Isoform 抗体
- Protein L-Myc 抗体
- Protein L 抗体
- Protein G 抗体
- Protein B-Myc 抗体
- Protein Arginine Methyltransferase 1 抗体
- Protein A 抗体
- Proteasome Subunit alpha 6 抗体
- Proteasome Subunit alpha 7 抗体
- Prostate Specific Antigen 抗体
- Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) 抗体
- Prostaglandin F2alpha 抗体
- Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L 抗体
- Protein Prenyltransferase alpha Subunit Repeat Containing 1 抗体
- Protein Quaking 抗体
- Protein Red 抗体
- Protein RNF21 抗体
- Protein Rta/BRLF1 抗体
- Protein S 抗体
- Protein Tob1 抗体
- Protein Tyrosine Phosphatase 抗体
- Protein tyrosine Phosphatase, Receptor Type, J 抗体
- Proteoglycan 3 抗体
- Proteoglycan 4 抗体
- Proteolipid Protein 1 抗体
- Prothrombin 抗体
- Prothrombin Fragment 1+2,F1+2 抗体
- Protocadherin 1 抗体
- Protocadherin 10 抗体
- Protocadherin 8 抗体
- Protocadherin 9 抗体
- Protocadherin gamma 12 抗体
You are here:
