Protein Phosphatase 4, Regulatory Subunit 2 产品
(Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
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Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage- dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).
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Protein Phosphatase 4, Regulatory Subunit 2 抗体
High quality antibodies with extensive validation data.
Protein Phosphatase 4, Regulatory Subunit 2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Protein Phosphatase 4, Regulatory Subunit 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7075284
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257426
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN1500387
Quantity
100 μL
Datasheet
Datasheet
Recommended Protein Phosphatase 4, Regulatory Subunit 2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6206801
Quantity
96 tests
Datasheet
Datasheet
Recommended Protein Phosphatase 4, Regulatory Subunit 2 蛋白
Latest Publications for our Protein Phosphatase 4, Regulatory Subunit 2 Products
: "PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN." in: European journal of cell biology, Vol. 91, Issue 8, pp. 662-74, (2012) (PubMed).: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, (2009) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
Synonyms and alternative names related to Protein Phosphatase 4, Regulatory Subunit 2
protein phosphatase 4 regulatory subunit 2 (PPP4R2), protein phosphatase 4, regulatory subunit 2 (Ppp4r2), protein phosphatase 4, regulatory subunit 2a (ppp4r2a), protein phosphatase 4 regulatory subunit 2 S homeolog (ppp4r2.S), protein phosphatase 4 regulatory subunit 2 (ppp4r2), protein phosphatase 4 regulatory subunit 2 L homeolog (ppp4r2.L), protein phosphatase 4, regulatory subunit 2b (ppp4r2b), BE691708, C230060M08Rik, fe11b04, PP4R2, ppp4r2, ppp4r2-B, wu:fa17h08, wu:fc23g05, wu:fe11b04Protein level used designations for Protein Phosphatase 4, Regulatory Subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2-A
- protein phosphatase 4, regulatory subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2-B
- Serine/threonine-protein phosphatase 4 regulatory subunit 2
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