Prostaglandin D2 Receptor 2 产品
(Prostaglandin D2 Receptor 2 (PTGDR2))
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This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011].
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Featured Prostaglandin D2 Receptor 2 Categories
Prostaglandin D2 Receptor 2 抗体
High quality antibodies with extensive validation data.
Recommended Prostaglandin D2 Receptor 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Application
IHC, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN1048827
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (3)
Cat. No.
ABIN7505894
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (3)
Cat. No.
ABIN7505895
Quantity
100 tests
Datasheet
Datasheet
Recommended Prostaglandin D2 Receptor 2 蛋白
Product
Reactivity
Source
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Cat. No.
Quantity
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Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491717
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3120396
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3119522
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Prostaglandin D2 Receptor 2 Products
: "Prostaglandin D2 effects and DP1 /DP2 receptor distribution in guinea pig urinary bladder out-flow region." in: Journal of cellular and molecular medicine, (2016) (PubMed).: "Depletion of major pathogenic cells in asthma by targeting CRTh2." in: JCI insight, Vol. 1, Issue 7, pp. e86689, (2016) (PubMed).
: "Receptors involved in the modulation of guinea pig urinary bladder motility by prostaglandin D2." in: British journal of pharmacology, Vol. 172, Issue 16, pp. 4024-37, (2015) (PubMed).
: "Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease. ..." in: Nature medicine, Vol. 21, Issue 5, pp. 467-75, (2015) (PubMed).
: "Role of prostaglandin D2 in mast cell activation-induced sensitization of esophageal vagal afferents." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 10, pp. G908-16, (2013) (PubMed).
: "Novel association between vasoactive intestinal peptide and CRTH2 receptor in recruiting eosinophils: a possible biochemical mechanism for allergic eosinophilic inflammation of the airways." in: The Journal of biological chemistry, Vol. 288, Issue 2, pp. 1374-84, (2013) (PubMed).
: "Tumor stroma reaction-related gene signature predicts clinical outcome in human hepatocellular carcinoma." in: Cancer science, Vol. 102, Issue 8, pp. 1522-31, (2011) (PubMed).
: "Mast cell-derived prostaglandin D2 controls hyaluronan synthesis in human orbital fibroblasts via DP1 activation: implications for thyroid eye disease." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 15794-804, (2010) (PubMed).
: "Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 4, pp. 2056-60, (2005) (PubMed).
: "Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced ..." in: The Journal of pharmacology and experimental therapeutics, Vol. 307, Issue 2, pp. 518-25, (2003) (PubMed).
Synonyms and alternative names related to Prostaglandin D2 Receptor 2
prostaglandin D2 receptor 2 (PTGDR2), prostaglandin D2 receptor 2 (Ptgdr2), CD294, CRTH2, Crth2, DL1R, DP2, GPR44, Gpr44, Grp45, Ptgdr2Protein level used designations for Prostaglandin D2 Receptor 2
- G protein-coupled receptor 44
- G-protein coupled receptor 44
- chemoattractant receptor homologous molecule expressed on T helper type 2 cells
- chemoattractant receptor-homologous molecule expressed on TH2 cells
- putative G-protein coupled receptor 44
- PGD2 receptor
- prostaglandin D2 receptor 2
- prostaglandin D2 receptor CRTH2
- G-protein coupled receptor
- chemoattractant receptor-homologous molecule expressed on Th2 cells
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