Prosaposin 抗体
(Prosaposin (PSAP))
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
recommended
PSAP 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4D5F4 unconjugated
recommended
recommended
Prosaposin 抗体 by Grade
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Prosaposin 抗体 by 适用
Find Prosaposin 抗体 for a variety of species such as anti-Human Prosaposin, anti-Mouse Prosaposin, anti-Rat Prosaposin. The species listed below are among those available. Click on a link to go to the corresponding products.
Prosaposin 抗体 by 抗体来源
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Prosaposin 抗体 by 克隆形成能力
Find available monoclonal or polyclonal Prosaposin 抗体. Click on a link to go to the corresponding products.
Prosaposin 抗体 by 克隆
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Validations
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Datasheet
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Datasheet
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Latest Publications for our Prosaposin 抗体
: "Serum prosaposin levels are increased in patients with advanced prostate cancer." in: The Prostate, Vol. 72, Issue 3, pp. 253-69, (2012) (PubMed).: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).
: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." in: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).
: "Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking." in: Human molecular genetics, Vol. 16, Issue 8, pp. 957-71, (2007) (PubMed).
Aliases for Prosaposin 抗体
prosaposin (PSAP) 抗体prosaposin (Psap) 抗体
prosaposin (psap) 抗体
prosaposin (LOC100011417) 抗体
prosaposin (LOC100304726) 抗体
prosaposin (LOC100526719) 抗体
surfactant protein A1 (SFTPA1) 抗体
AI037048 抗体
cb759 抗体
GLBA 抗体
PSAP 抗体
PSP-A 抗体
SAP1 抗体
SFTPA1B 抗体
SGP-1 抗体
SGP1A 抗体
SP-A 抗体
wu:fa14a06 抗体
wu:fb36e02 抗体
wu:fb58g07 抗体
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