Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq, Jul 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Latest Publications for our Proadrenomedullin Products
Kannan, Rao, Mithra, Dhanashree, Baliga, Bhat: "Diagnostic and Prognostic Validity of Proadrenomedullin among Neonates with Sepsis in Tertiary Care Hospitals of Southern India." in: International journal of pediatrics, Vol. 2018, pp. 7908148, (2018) (PubMed).
Oncel, Dilmen, Erdeve, Ozdemir, Calisici, Yurttutan, Canpolat, Oguz, Uras: "Proadrenomedullin as a prognostic marker in neonatal sepsis." in: Pediatric research, Vol. 72, Issue 5, pp. 507-12, (2012) (PubMed).
Synonyms and alternative names related to Proadrenomedullin
adrenomedullin (ADM), adrenomedullin (adm), ADM
Protein level used designations for Proadrenomedullin