PRKDC 产品
(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
Categories
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010].
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Featured PRKDC Categories
PRKDC 抗体
High quality antibodies with extensive validation data.
PRKDC ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PRKDC 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PRKDC 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IF, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN519209
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC
Validations
- (2)
- (5)
Cat. No.
ABIN969366
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN6241643
Quantity
100 μL
Datasheet
Datasheet
Recommended PRKDC ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958940
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1130280
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1130281
Quantity
96 tests
Datasheet
Datasheet
Recommended PRKDC 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1316293
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399958
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5710145
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PRKDC Products
: "Interactome of the Autoimmune Risk Protein ANKRD55." in: Frontiers in immunology, Vol. 10, pp. 2067, (2019) (PubMed).: "DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination." in: Molecular cell, Vol. 65, Issue 4, pp. 671-684.e5, (2017) (PubMed).
: "The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites." in: Nature communications, Vol. 8, pp. 15751, (2017) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2." in: Molecular biology of the cell, Vol. 28, Issue 1, pp. 192-200, (2016) (PubMed).
: "Identification of PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide) as an essential gene for colorectal cancer (CRCs) cells." in: Gene, Vol. 584, Issue 1, pp. 90-6, (2016) (PubMed).
: "Quantification of the host response proteome after herpes simplex virus type 1 infection." in: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).
: "Mutual regulation between DNA-PKcs and Snail1 leads to increased genomic instability and aggressive tumor characteristics." in: Cell death & disease, Vol. 4, pp. e517, (2013) (PubMed).
: "Accumulation of DNA damage-induced chromatin alterations in tissue-specific stem cells: the driving force of aging?" in: PLoS ONE, Vol. 8, Issue 5, pp. e63932, (2013) (PubMed).
: "Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy." in: PLoS ONE, Vol. 7, Issue 5, pp. e38165, (2012) (PubMed).
Synonyms and alternative names related to PRKDC
protein kinase, DNA-activated, catalytic polypeptide (PRKDC), protein kinase, DNA-activated, catalytic polypeptide L homeolog (prkdc.L), DNA-dependent protein kinase catalytic subunit (LOC100633457), protein kinase, DNA activated, catalytic polypeptide (Prkdc), AI326420, AU019811, DNA-PKcs, DNA-PKCS, dna-pkcs, DNAPDcs, DNAPK, dnapk, DNPK1, dnpk1, DOXNPH, dxnph, HYRC, hyrc, HYRC1, hyrc1, p350, p460, PRKDC, prkdc-A, scid, slip, XRCC7, xrcc7Protein level used designations for PRKDC
- DNA-PK catalytic subunit
- DNA-dependent protein kinase catalytic subunit
- hyper-radiosensitivity of murine scid mutation, complementing 1
- p460
- protein kinase, DNA-activated, catalytic polypeptide
- DNA-PKcs
- protein kinase catalytic subunit (DNA-dependent protein kinase)
- DNA-activated protein kinase catalytic polypeptide
- DNA-dependent protein kinase catalytic subunit-like
- doxorubicin nephropathy
- severe combined immunodeficiency
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