PRKAA1 产品
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
Categories
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
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Featured PRKAA1 Categories
PRKAA1 抗体
High quality antibodies with extensive validation data.
PRKAA1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PRKAA1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PRKAA1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
- (13)
Cat. No.
ABIN3021788
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440413
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (7)
Cat. No.
ABIN7265094
Quantity
200 μL
Datasheet
Datasheet
Recommended PRKAA1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN5526721
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
Cat. No.
ABIN5526722
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6969725
Quantity
96 tests
Datasheet
Datasheet
Recommended PRKAA1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124656
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316204
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316206
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PRKAA1 Products
: "Fatty Acids Regulate Porcine Reproductive and Respiratory Syndrome Virus Infection via the AMPK-ACC1 Signaling Pathway." in: Viruses, Vol. 11, Issue 12, (2020) (PubMed).: "Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 313, (2019) (PubMed).
: "STIM2 interacts with AMPK and regulates calcium-induced AMPK activation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 2, pp. 2957-2970, (2019) (PubMed).
: "High CO2 downregulates skeletal muscle protein anabolism via AMPKα2-mediated depressed ribosomal biogenesis." in: American journal of respiratory cell and molecular biology, (2019) (PubMed).
: "A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity." in: JCI insight, Vol. 4, Issue 13, (2019) (PubMed).
: "Protective effects of melatonin against nicotine-induced disorder of mouse early folliculogenesis." in: Aging, Vol. 10, Issue 3, pp. 463-480, (2019) (PubMed).
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).
: "Antidiabetic activities of entagenic acid in type 2 diabetic db/db mice and L6 myotubes via AMPK/GLUT4 pathway." in: Journal of ethnopharmacology, Vol. 211, pp. 366-374, (2018) (PubMed).
: "CO suppresses prostate cancer cell growth by directly targeting LKB1/AMPK/mTOR pathway in vitro and in vivo." in: Urologic oncology, Vol. 36, Issue 6, pp. 312.e1-312.e8, (2018) (PubMed).
: "Alternative polyadenylation drives genome-to-phenome information detours in the AMPKα1 and AMPKα2 knockout mice." in: Scientific reports, Vol. 8, Issue 1, pp. 6462, (2018) (PubMed).
Synonyms and alternative names related to PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1 (PRKAA1), protein kinase, AMP-activated, alpha 1 catalytic subunit (prkaa1), protein kinase, AMP-activated, alpha 1 catalytic subunit (PRKAA1), protein kinase AMP-activated catalytic subunit alpha 1 (Prkaa1), protein kinase, AMP-activated, alpha 1 catalytic subunit (Prkaa1), protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog (prkaa1.L), AI194361, AI450832, AL024255, AMPK, ampk, AMPK1, AMPKa1, ampka1, AMPKalpha1, C130083N04Rik, cb116, im:7154392, PRKAA1, sb:cb130, wu:fa94c10Protein level used designations for PRKAA1
- 5'-AMP-activated protein kinase catalytic subunit alpha-1
- 5'-AMP-activated protein kinase, catalytic alpha-1 chain
- ACACA kinase
- AMP -activate kinase alpha 1 subunit
- AMP-activated protein kinase, catalytic, alpha-1
- AMPK alpha 1
- AMPK subunit alpha-1
- HMGCR kinase
- acetyl-CoA carboxylase kinase
- hydroxymethylglutaryl-CoA reductase kinase
- tau-protein kinase PRKAA1
- 5'-AMP-activated protein kinase alpha-1 catalytic subunit
- AMPKalpha1
- ampka1
- 5'-AMP-activated protein kinase alpha 1 catalytic subunit
- 63 kDa subunit
- AMPK 63 kDa subunit
- AMPK alpha-1 chain
- AMP-activated protein kinase, alpha 1 catalytic subunit
- 5'-AMP-activated protein kinase catalyti subunit alpha-1-like protein
- AMPK-activated protein kinase alpha-1 subunit
- protein kinase, AMP-activated, alpha 1 catalytic subunit
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