PRG2 产品
(Bone Marrow Proteoglycan (PRG2))
Categories
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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Featured PRG2 Categories
PRG2 抗体
High quality antibodies with extensive validation data.
PRG2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PRG2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PRG2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3016204
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6264418
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7145674
Quantity
100 μL
Datasheet
Datasheet
Recommended PRG2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965181
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975292
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6975668
Quantity
96 tests
Datasheet
Datasheet
Recommended PRG2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316187
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7318206
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN4370675
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PRG2 Products
: "Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis." in: Digestive diseases and sciences, Vol. 65, Issue 1, pp. 141-149, (2020) (PubMed).: "Rescue of rhesus macaques from the lethality of aerosolized ricin toxin." in: JCI insight, Vol. 4, Issue 1, (2019) (PubMed).
: "Pathophysiological mechanisms of itch in bullous pemphigoid." in: Journal of the American Academy of Dermatology, (2019) (PubMed).
: "Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages." in: The Journal of investigative dermatology, (2019) (PubMed).
: "Impact of neonatal hypoxia-ischaemia on oligodendrocyte survival, maturation and myelinating potential." in: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 207-222, (2018) (PubMed).
: "Eosinophilic inflammation in lymph nodes of dogs with visceral leishmaniasis." in: Parasite immunology, Vol. 40, Issue 8, pp. e12567, (2018) (PubMed).
: "Preeclampsia: novel insights from global RNA profiling of trophoblast subpopulations." in: American journal of obstetrics and gynecology, Vol. 217, Issue 2, pp. 200.e1-200.e17, (2017) (PubMed).
: "Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus)." in: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2016) (PubMed).
: "Impaired duodenal mucosal integrity and low-grade inflammation in functional dyspepsia." in: Gut, Vol. 63, Issue 2, pp. 262-71, (2014) (PubMed).
Synonyms and alternative names related to PRG2
proteoglycan 2, bone marrow (Prg2), proteoglycan 2 (Prg2), proteoglycan 2, pro eosinophil major basic protein (PRG2), BMPG, MBP, MBP1, mMBP, mMBP-1Protein level used designations for PRG2
- BMPG
- bone marrow proteoglycan
- major basic protein 1
- eosinophil major basic protein
- bone-marrow proteoglycan
- eosinophil granule major basic protein
- natural killer cell activator
- proteoglycan 2 preproprotein
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