PREX1 产品
(Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))
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The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008].
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Featured PREX1 Categories
PREX1 抗体
High quality antibodies with extensive validation data.
PREX1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended PREX1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (5)
Cat. No.
ABIN656506
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7163177
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN6264416
Quantity
100 μL
Datasheet
Datasheet
Recommended PREX1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969255
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6233636
Quantity
96 tests
Datasheet
Datasheet
Recommended PREX1 蛋白
Latest Publications for our PREX1 Products
: "P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments." in: PLoS ONE, Vol. 8, Issue 1, pp. e53982, (2013) (PubMed).: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
: "P-Rex1 is required for efficient melanoblast migration and melanoma metastasis. ..." in: Nature communications, Vol. 2, pp. 555, (2011) (PubMed).
: "Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis." in: Oncogene, Vol. 28, Issue 16, pp. 1853-63, (2009) (PubMed).
Synonyms and alternative names related to PREX1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog (prex1.L), phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1), phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (prex1), phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (prex1), phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 (Prex1), G630042G04, MGC68772, P-REX1, RGD1306534, Setd6Protein level used designations for PREX1
- phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
- phosphatidylinositol 3,4,5-trisphosphate-dependent RAC exchanger 1
- phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein-like
- phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
- ptdIns(3,4,5)-dependent Rac exchanger 1
- SET domain containing 6
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- Pre-mRNA Branch Site Protein p14
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