PPT1 产品
(Palmitoyl-Protein Thioesterase 1 (PPT1))
Categories
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008].
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Featured PPT1 Categories
PPT1 抗体
High quality antibodies with extensive validation data.
PPT1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PPT1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPT1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (7)
Cat. No.
ABIN1490802
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
- (5)
Cat. No.
ABIN1944801
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (3)
Cat. No.
ABIN4913200
Quantity
100 μL
Datasheet
Datasheet
Recommended PPT1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951472
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1146898
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1146899
Quantity
96 tests
Datasheet
Datasheet
Recommended PPT1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316094
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7491183
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7415467
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PPT1 Products
: "Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses." in: Orphanet journal of rare diseases, Vol. 13, Issue 1, pp. 54, (2019) (PubMed).: "Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146466, (2016) (PubMed).
: "Quantitative analysis of PPT1 interactome in human neuroblastoma cells." in: Data in brief, Vol. 4, pp. 207-16, (2015) (PubMed).
: "The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting." in: Molecular and cellular biology, Vol. 32, Issue 10, pp. 1855-66, (2012) (PubMed).
: "The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37957-64, (2003) (PubMed).
: "The neuronal ceroid lipofuscinoses: mutations in different proteins result in similar disease." in: Neuromolecular medicine, Vol. 1, Issue 2, pp. 111-24, (2002) (PubMed).
: "Neuronal ceroid lipofuscinoses caused by defects in soluble lysosomal enzymes (CLN1 and CLN2)." in: Current molecular medicine, Vol. 2, Issue 5, pp. 423-37, (2002) (PubMed).
: "Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 9, pp. 4316-9, (1996) (PubMed).
: "cDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis." in: Genomics, Vol. 34, Issue 3, pp. 317-22, (1996) (PubMed).
: "Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis." in: Nature, Vol. 376, Issue 6541, pp. 584-7, (1995) (PubMed).
Synonyms and alternative names related to PPT1
palmitoyl-protein thioesterase 1 (PPT1), palmitoyl-protein thioesterase 1 (MGYG_00692), palmitoyl-protein thioesterase 1 (Ppt1), Palmitoyl-protein thioesterase 1 (ppt-1), palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) (ppt1), palmitoyl-protein thioesterase 1 L homeolog (ppt1.L), 9530043G02Rik, AA960502, C77813, CLN1, D4Ertd184e, INCL, PPT, Ppt, PPT-1, ppt1, wu:fj17f04, zgc:63969Protein level used designations for PPT1
- ceroid-palmitoyl-palmitoyl-protein thioesterase 1
- palmitoyl-protein hydrolase 1
- palmitoyl-protein thioesterase 1
- PPT-1
- palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
- palmitoyl protein thioesterase
- Palmitoyl-protein hydrolase 1
- palmitoyl-protein thioesterase 1 L homeolog
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