PPP2R4 产品
(Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
Categories
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured PPP2R4 Categories
PPP2R4 抗体
High quality antibodies with extensive validation data.
PPP2R4 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PPP2R4 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPP2R4 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC, FACS
Validations
- (2)
- (6)
Cat. No.
ABIN969557
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN519124
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IF
Validations
- (2)
- (4)
Cat. No.
ABIN1682265
Quantity
100 μg
Datasheet
Datasheet
Recommended PPP2R4 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969737
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958945
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1157491
Quantity
96 tests
Datasheet
Datasheet
Recommended PPP2R4 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316044
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316042
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406794
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PPP2R4 Products
: "Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis." in: Theranostics, Vol. 7, Issue 4, pp. 1036-1046, (2017) (PubMed).: "Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy." in: EBioMedicine, Vol. 17, pp. 45-56, (2017) (PubMed).
: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).
: "Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1140-52, (2010) (PubMed).
: "Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling." in: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 12862-9, (2008) (PubMed).
: "A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo." in: Genes & development, Vol. 17, Issue 17, pp. 2138-50, (2003) (PubMed).
Synonyms and alternative names related to PPP2R4
protein phosphatase 2 phosphatase activator (PTPA), protein phosphatase 2 protein activator (Ptpa), protein phosphatase 2 phosphatase activator (Ptpa), protein phosphatase 2 phosphatase activator (ptpa), protein phosphatase 2 phosphatase activator L homeolog (ptpa.L), 2610042B21Rik, C77440, fc23d07, N28142, PP2A, pp2a, Ppp2r4, ppp2r4, ppp2r4.L, PR53, pr53, PTPA, ptpa, PTPRA, wu:fc23d07, zgc:92766Protein level used designations for PPP2R4
- PP2A phosphatase activator
- PP2A subunit B' isoform PR53
- phosphotyrosyl phosphatase activator
- protein phosphatase 2A, regulatory subunit B' (PR 53)
- serine/threonine-protein phosphatase 2A activator
- serine/threonine-protein phosphatase 2A regulatory subunit B'
- PP2A, subunit B', PR53 isoform
- PTPA
- serine/threonine-protein phosphatase 2A regulatory subunit 4
- protein tyrosine phosphatase, receptor type, A
- protein phosphatase 2 regulatory subunit 4
- protein phosphatase 2A activator, regulatory subunit 4
- protein phosphatase 2A regulatory subunit 4
- protein phosphatase 2A, regulatory subunit B (PR 53)
- protein phosphatase 2 phosphatase activator L homeolog
- protein phosphatase 2A regulatory subunit 4 L homeolog
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