PPP2R1A 抗体
(Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
recommended
PPP2R1A 适用: 人, 小鼠 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
recommended
recommended
PPP2R1A 适用: 人, 小鼠, 大鼠, 猴, Drosophila melanogaster WB, IF, FACS 宿主: 兔 Polyclonal unconjugated
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Popular PPP2R1A 抗体
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Reactivity
Application
Validations
Cat. No.
Quantity
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Reactivity
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Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
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Cat. No.
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Quantity
100 μL
Datasheet
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Reactivity
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Application
WB, ELISA, PLA
Validations
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Cat. No.
ABIN519115
Quantity
100 μg
Datasheet
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Reactivity
Drosophila melanogaster, Human, Monkey, Mouse, Rat
Application
WB, IF, FACS
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, ELISA, IHC, IHC (p)
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Cat. No.
ABIN961593
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat, Xenopus laevis, Zebrafish (Danio rerio)
Application
WB, IHC, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
IF
Validations
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Cat. No.
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Quantity
200 μL
Datasheet
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Reactivity
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Application
WB
Validations
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Cat. No.
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Quantity
100 μg
Datasheet
Datasheet
Reactivity
Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
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Cat. No.
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Datasheet
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Cat. No.
ABIN1881682
Quantity
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Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
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Cat. No.
ABIN2774161
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN873062
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN911967
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our PPP2R1A 抗体
: "PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." in: Cells, Vol. 9, Issue 1, (2020) (PubMed).: "Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma." in: Science (New York, N.Y.), Vol. 330, Issue 6001, pp. 228-31, (2010) (PubMed).
: "Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells." in: Nature cell biology, Vol. 12, Issue 9, pp. 886-93, (2010) (PubMed).
: "Protein phosphatase 2A subunit gene haplotypes and proliferative breast disease modify breast cancer risk." in: Cancer, Vol. 116, Issue 1, pp. 8-19, (2010) (PubMed).
: "Hypoxia-activated Smad3-specific dephosphorylation by PP2A." in: The Journal of biological chemistry, Vol. 285, Issue 6, pp. 3740-9, (2010) (PubMed).
: "HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2622-7, (2010) (PubMed).
: "A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 10, pp. 1012-21, (2009) (PubMed).
: "Reduced expression of the regulatory A subunit of serine/threonine protein phosphatase 2A in human breast cancer MCF-7 cells." in: International journal of oncology, Vol. 23, Issue 5, pp. 1263-8, (2003) (PubMed).
: "Absence of PPP2R1A mutations in Wilms tumor." in: Oncogene, Vol. 20, Issue 16, pp. 2050-4, (2001) (PubMed).
: "HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25." in: Virology, Vol. 287, Issue 2, pp. 359-70, (2001) (PubMed).
Aliases for PPP2R1A 抗体
protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A) 抗体protein phosphatase 2 scaffold subunit A alpha (Ppp2r1a) 抗体
protein phosphatase 2 regulatory subunit A, alpha L homeolog (ppp2r1a.L) 抗体
protein phosphatase 2 regulatory subunit A, alpha (ppp2r1a) 抗体
protein phosphatase 2, regulatory subunit A, beta a (ppp2r1ba) 抗体
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (LOC583227) 抗体
protein phosphatase 2, regulatory subunit A, alpha isoform (Ppp2r1a) 抗体
protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A) 抗体
protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a) 抗体
protein phosphatase 2 regulatory subunit A, alpha S homeolog (ppp2r1a.S) 抗体
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