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PPP2CA 产品

(Protein Phosphatase 2, Catalytic Subunit, alpha Isozyme (PPP2CA))

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This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].

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Featured PPP2CA Categories

PPP2CA 抗体

High quality antibodies with extensive validation data.

PPP2CA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PPP2CA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPP2CA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IHC (p), IP, ICC
Validations
  • (8)
Cat. No. ABIN2856333
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN6146078
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7169266
Quantity 100 μg
Datasheet Datasheet

Recommended PPP2CA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN419681
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380253
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended PPP2CA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316010
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505262
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086492
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PPP2CA Products

Yong, YuFeng, Guang: "Association between PPP2CA expression and colorectal cancer prognosis tumor marker prognostic study." in: International journal of surgery (London, England), Vol. 59, pp. 80-89, (2019) (PubMed).

Zhang, Wang, Qin, Wang, Liu, White, Zheng: "PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer." in: EBioMedicine, Vol. 2, Issue 12, pp. 1944-56, (2016) (PubMed).

Hung, Wang, Chen, Chu, Hsiao, Tai, Chao, Yu, Shiau, Chen: "SET antagonist enhances the chemosensitivity of non-small cell lung cancer cells by reactivating protein phosphatase 2A." in: Oncotarget, Vol. 7, Issue 1, pp. 638-55, (2016) (PubMed).

Tay, Liu, Chi, Jin, Jiang, Guo, Verrills, Tseng, Zhang: "Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720." in: Pigment cell & melanoma research, Vol. 28, Issue 2, pp. 171-83, (2015) (PubMed).

Bhardwaj, Singh, Srivastava, Arora, Hyde, Andrews, Grizzle, Singh: "Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model." in: British journal of cancer, Vol. 110, Issue 8, pp. 2000-10, (2014) (PubMed).

Ma, Li, Wang, Gong, Zhang, Li, Ji, Liu, Chen, Xiang: "Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways." in: Regulatory peptides, Vol. 181, pp. 9-16, (2013) (PubMed).

Wu, Reardon, Storey: "Effects of hibernation on regulation of mammalian protein phosphatase type-2-A." in: Cryobiology, Vol. 66, Issue 3, pp. 267-74, (2013) (PubMed).

Benziane, Björnholm, Pirkmajer, Austin, Kotova, Viollet, Zierath, Chibalin: "Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23451-63, (2012) (PubMed).

Tay, Jin, Tseng, Jiang, Ye, Thorne, Liu, Guo, Verrills, Hersey, Zhang: "Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress." in: Cell death & disease, Vol. 3, pp. e337, (2012) (PubMed).

Li, Huang, Liang, Fu, Guo, Xu: "Microcystin-LR (MCLR) induces a compensation of PP2A activity mediated by ?4 protein in HEK293 cells." in: International journal of biological sciences, Vol. 7, Issue 6, pp. 740-52, (2011) (PubMed).

Synonyms and alternative names related to PPP2CA

protein phosphatase 2 catalytic subunit alpha (PPP2CA), protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Ppp2ca), protein phosphatase 2, catalytic subunit, alpha isozyme (Ppp2ca), protein phosphatase 2 catalytic subunit alpha L homeolog (ppp2ca.L), protein phosphatase 2, catalytic subunit, beta isozyme (ppp2cb), serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (LOC471633), protein phosphatase 2, catalytic subunit, alpha isozyme (ppp2ca), protein phosphatase 2 catalytic subunit alpha (Ppp2ca), PP2A, Pp2a1, PP2Ac, pp2ac, PP2CA, PP2Calpha, R75353, RP-C, zgc:110641

Protein level used designations for PPP2CA

  • PP2A-alpha
  • protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  • protein phosphatase 2A catalytic subunit, alpha isoform
  • replication protein C
  • serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform
  • serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
  • protein phosphatase 2a, catalytic subunit, alpha isoform
  • protein phosphatase 2, catalytic subunit, alpha isoform
  • protein phosphatase-2A-alpha
  • protein phosphatase 2A alpha subunit
  • protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
  • type 2A protein phosphatase catalytic subunit
  • protein phosphatase 2, catalytic subunit, beta isoform
  • protein phosphatase 2, catalytic subunit, alpha isozyme
  • serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like
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