PPP1R12A 抗体
(Myosin Phosphatase, Target Subunit 1 (PPP1R12A))
Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009].
recommended
Verified PPP1R12A 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
recommended
recommended
PPP1R12A 抗体 by Grade
Find PPP1R12A 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
PPP1R12A 抗体 by 应用范围
Find PPP1R12A 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.
PPP1R12A 抗体 by 抗体来源
Find PPP1R12A 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
PPP1R12A 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PPP1R12A 抗体. Click on a link to go to the corresponding products.
PPP1R12A 抗体 by 克隆
Find PPP1R12A 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular PPP1R12A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF, FACS
Validations
- (9)
Cat. No.
ABIN6391349
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (6)
Cat. No.
ABIN6146059
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (7)
Cat. No.
ABIN3043902
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (1)
- (3)
Cat. No.
ABIN6263491
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, FACS
Validations
- (3)
Cat. No.
ABIN744068
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7182058
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (2)
Cat. No.
ABIN6242457
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN3185745
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN3182548
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN6146060
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Chicken, Human, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7303414
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
Cat. No.
ABIN744083
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6242461
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6242460
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN6242459
Quantity
200 μL
Datasheet
Datasheet
Latest Publications for our PPP1R12A 抗体
: "Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica." in: Scientific reports, Vol. 6, pp. 32257, (2018) (PubMed).: "Icariin promotes proliferation and osteogenic differentiation of rat adipose-derived stem cells by activating the RhoA-TAZ signaling pathway." in: Biomedicine & pharmacotherapy, Vol. 88, pp. 384-394, (2017) (PubMed).
: "The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia." in: Neural regeneration research, Vol. 10, Issue 9, pp. 1441-9, (2015) (PubMed).
: "Chlamydia trachomatis inclusion membrane protein CT228 recruits elements of the myosin phosphatase pathway to regulate release mechanisms." in: Cell reports, Vol. 3, Issue 6, pp. 1921-31, (2013) (PubMed).
: "Role of myosin phosphatase isoforms in cGMP-mediated smooth muscle relaxation." in: The Journal of biological chemistry, Vol. 276, Issue 40, pp. 37250-7, (2001) (PubMed).
: "Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)" in: Science (New York, N.Y.), Vol. 273, Issue 5272, pp. 245-8, (1996) (PubMed).
: "Molecular cloning of cDNA encoding the 110 kDa and 21 kDa regulatory subunits of smooth muscle protein phosphatase 1M." in: FEBS letters, Vol. 356, Issue 1, pp. 51-5, (1995) (PubMed).
Aliases for PPP1R12A 抗体
protein phosphatase 1, regulatory (inhibitor) subunit 12A (Ppp1r12a) 抗体protein phosphatase 1 regulatory subunit 12A (PPP1R12A) 抗体
protein phosphatase 1, regulatory subunit 12A (Ppp1r12a) 抗体
1200015F06Rik 抗体
5730577I22Rik 抗体
AA792106 抗体
AV099298 抗体
D10Ertd625e 抗体
M110 抗体
M130 抗体
MBS 抗体
MBSP 抗体
Mypt1 抗体
MYPT1 抗体
您还需要查找其他产品吗？
You are here:
