PPARGC1B 产品
(Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
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The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
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Featured PPARGC1B Categories
PPARGC1B 抗体
High quality antibodies with extensive validation data.
PPARGC1B ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended PPARGC1B 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN872354
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (4)
Cat. No.
ABIN2683008
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7269253
Quantity
100 μL
Datasheet
Datasheet
Recommended PPARGC1B ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN4993641
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6220445
Quantity
96 tests
Datasheet
Datasheet
Recommended PPARGC1B 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505260
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094725
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PPARGC1B Products
: "Functional Characterization of Exonic Variants of the PPARGC1B Gene in Coregulation of Estrogen Receptor Alpha." in: DNA and cell biology, Vol. 35, Issue 7, pp. 314-21, (2016) (PubMed).: "Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 37, pp. 11696-701, (2015) (PubMed).
: "Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting ..." in: Arthritis research & therapy, Vol. 16, Issue 5, pp. 472, (2015) (PubMed).
: "Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury." in: Cardiovascular research, Vol. 97, Issue 2, pp. 251-61, (2013) (PubMed).
: "Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 1, pp. 122-8, (2013) (PubMed).
: "Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform." in: Molecular and cellular endocrinology, Vol. 369, Issue 1-2, pp. 150-60, (2013) (PubMed).
: "Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis." in: Journal of lipid research, Vol. 53, Issue 3, pp. 358-67, (2012) (PubMed).
: "Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance." in: American journal of physiology. Endocrinology and metabolism, Vol. 297, Issue 4, pp. E898-906, (2010) (PubMed).
: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
: "Rapid exercise-induced changes in PGC-1alpha mRNA and protein in human skeletal muscle." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 105, Issue 4, pp. 1098-105, (2008) (PubMed).
Synonyms and alternative names related to PPARGC1B
PPARG coactivator 1 beta (PPARGC1B), peroxisome proliferative activated receptor, gamma, coactivator 1 beta (Ppargc1b), PPARG coactivator 1 beta (Ppargc1b), 4631412G21Rik, ERRL1, Perc, PERC, PGC-1(beta), PGC1B, PGC1beta, PPARGC1BProtein level used designations for PPARGC1B
- peroxisome proliferator-activated receptor gamma, coactivator 1 beta
- peroxisome proliferator-activated receptor gamma coactivator 1-beta-like
- ERR ligand 1
- PGC-1-beta
- PGC-1beta
- PGC-1beta/ERRL1
- PPAR gamma coactivator-1beta protein
- PPAR-gamma coactivator 1-beta
- PPARGC-1-beta
- peroxisome proliferator-activated receptor gamma coactivator 1 beta
- peroxisome proliferator-activated receptor gamma coactivator 1-beta
- peroxisome proliferative activated receptor, gamma, coactivator 1 beta
- peroxisome proliferator-activated receptor gamma coactivator 1beta-2a
- PGC-1-related estrogen receptor alpha coactivator
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