PPARGC1A 产品
(Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A))
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The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008].
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Featured PPARGC1A Categories
PPARGC1A 抗体
High quality antibodies with extensive validation data.
Recommended PPARGC1A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Pig, Rat
Application
WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p)
Validations
- (2)
Cat. No.
ABIN873223
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Pig, Rat
Application
WB, ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN910849
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Pig, Rat
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN910841
Quantity
100 μL
Datasheet
Datasheet
Recommended PPARGC1A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7498303
Quantity
200 μg
Datasheet
Datasheet
Latest Publications for our PPARGC1A Products
: "LONP1 induction by SRT1720 attenuates mitochondrial dysfunction against high glucose induced neurotoxicity in PC12 cells." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 62, pp. 104695, (2020) (PubMed).: "Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis." in: Cell metabolism, Vol. 31, Issue 1, pp. 189-206.e8, (2020) (PubMed).
: "Ubiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise." in: Food & function, Vol. 11, Issue 9, pp. 7523-7531, (2020) (PubMed).
: "Resveratrol Improves Muscle Atrophy by Modulating Mitochondrial Quality Control in STZ-Induced Diabetic Mice." in: Molecular nutrition & food research, Vol. 62, Issue 9, pp. e1700941, (2019) (PubMed).
: "Secretory phospholipase A2 group IIA enhances the metabolic rate and increases glucose utilization in response to thyroid hormone." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 1, pp. 738-749, (2019) (PubMed).
: "A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis." in: Neurochemical research, Vol. 44, Issue 1, pp. 22-37, (2019) (PubMed).
: "Recombinant human glucagon-like peptide-1 protects against chronic intermittent hypoxia by improving myocardial energy metabolism and mitochondrial biogenesis." in: Molecular and cellular endocrinology, Vol. 481, pp. 95-103, (2019) (PubMed).
: "Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro-elongation phenotype." in: Acta physiologica (Oxford, England), Vol. 225, Issue 4, pp. e13216, (2019) (PubMed).
: "SIRT1 overexpression attenuates offspring metabolic and liver disorders as a result of maternal high-fat feeding." in: The Journal of physiology, Vol. 597, Issue 2, pp. 467-480, (2019) (PubMed).
: "p53/BNIP3-dependent mitophagy limits glycolytic shift in radioresistant cancer." in: Oncogene, (2019) (PubMed).
Synonyms and alternative names related to PPARGC1A
PPARG coactivator 1 alpha (PPARGC1A), peroxisome proliferative activated receptor, gamma, coactivator 1 alpha (Ppargc1a), PPARG coactivator 1 alpha (Ppargc1a), PPARG coactivator 1 alpha S homeolog (ppargc1a.S), A830037N07Rik, AVPGC-1ALPHA, ENSMUSG00000079510, Gm11133, LEM6, PGC-1, PGC-1(alpha), Pgc-1alpha, PGC-1v, Pgc1, PGC1, PGC1A, Pgco1, PPARGC1, Ppargc1, PPARGC1AProtein level used designations for PPARGC1A
- peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- PPAR-gamma coactivator
- peroxisome proliferator activated receptor gamma coactivator-1
- PGC-1-alpha
- PPAR Gamma Coactivator-1
- PPAR gamma coactivator variant form
- PPAR-gamma coactivator 1-alpha
- PPARGC-1-alpha
- Pgc-1alphaa
- peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- L-PGC-1alpha
- ligand effect modulator-6
- peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4
- peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext
- peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a
- peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5
- peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT
- peroxisome proliferative activated receptor, gamma, coactivator 1
- peroxisome proliferator activated receptor gamma coactivator 1 alpha
- PGC-1alpha
- peroxisome proliferative activated receptor gamma coactivator 1
- peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
- proliferator-activated receptor gamma coactivator 1 alpha
- peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
- peroxisome-proliferator-activated receptor-gamma co-activator-1
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