PPARD 产品
(Peroxisome Proliferator-Activated Receptor delta (PPARD))
Categories
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. Knockout studies in mice suggested the role of this protein in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010].
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Featured PPARD Categories
PPARD 抗体
High quality antibodies with extensive validation data.
PPARD ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PPARD 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PPARD 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (1)
- (4)
Cat. No.
ABIN562332
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA
Validations
- (1)
- (3)
Cat. No.
ABIN105799
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN519066
Quantity
100 μg
Datasheet
Datasheet
Recommended PPARD ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969235
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958501
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958502
Quantity
96 tests
Datasheet
Datasheet
Recommended PPARD 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315833
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315832
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505069
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PPARD Products
: "Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1." in: PLoS ONE, Vol. 12, Issue 8, pp. e0181052, (2017) (PubMed).: "Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy)." in: Human molecular genetics, Vol. 25, Issue 11, pp. 2194-2207, (2016) (PubMed).
: "PPARβ/δ and γ in a rat model of Parkinson's disease: possible involvement in PD symptoms." in: Journal of cellular biochemistry, Vol. 116, Issue 5, pp. 844-55, (2015) (PubMed).
: "Reactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell Formation." in: The Journal of biological chemistry, Vol. 290, Issue 51, pp. 30306-20, (2015) (PubMed).
: "PPARβ/δ regulates glucocorticoid- and sepsis-induced FOXO1 activation and muscle wasting." in: PLoS ONE, Vol. 8, Issue 3, pp. e59726, (2013) (PubMed).
: "Proteome changes in the myocardium of experimental chronic diabetes and hypertension: role of PPAR? in the associated hypertrophy." in: Journal of proteomics, Vol. 75, Issue 6, pp. 1816-29, (2012) (PubMed).
: "Biological function and prognostic significance of peroxisome proliferator-activated receptor ? in rectal cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 11, pp. 3760-70, (2011) (PubMed).
: "Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats." in: American journal of physiology. Endocrinology and metabolism, Vol. 298, Issue 6, pp. E1140-9, (2010) (PubMed).
: "Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells." in: Oncogene, Vol. 29, Issue 4, pp. 516-26, (2010) (PubMed).
: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
Synonyms and alternative names related to PPARD
peroxisome proliferator activated receptor delta (PPARD), peroxisome proliferator activator receptor delta (Ppard), peroxisome proliferator activated receptor delta S homeolog (ppard.S), peroxisome proliferator activated receptor delta (ppard), peroxisome proliferator-activated receptor delta (Ppard), peroxisome proliferator activated receptor delta (Ppard), FAAR, NR1C2, Nr1c2, NUC-1, NUC1, NUCI, NUCII, PPAR-beta, PPAR-D/B, PPAR-delta, PPARB, Pparb, pparb, Pparb/d, PPARBETA, ppard, PPARD, PPARdelta, PPAR[b]Protein level used designations for PPARD
- PPAR-beta
- PPAR-delta
- nuclear hormone receptor 1
- nuclear receptor subfamily 1 group C member 2
- peroxisome proliferator-activated nuclear receptor beta/delta variant 2
- peroxisome proliferator-activated receptor beta
- PPARdelta/beta
- Peroxisome proliferator-activated receptor beta
- peroxisome proliferator-activated receptor delta
- peroxisome proliferative activated receptor, delta
- peroxisome proliferator-activated receptor delta-like
- peroxisome proliferator activated receptor delta
- peroxisome proliferator activator receptor beta
- peroxisome proliferator activator receptor, delta
- peroxisome proliferator activator receptor delta
- peroxisome proliferator activated receptor delta/beta
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