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POU5F3.3 蛋白

(POU Class 5 Homeobox 3, Gene 3 (POU5F3.3))
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Antagonizes the activity of nodal/activin signaling during gastrulation to suppress mesendoderm formation. Acts maternally to inhibit vegt and beta-catenin-activated gene transcription, probably by forming a transcriptional repression complex on the promoters of target genes. Binds to an octamer motif in interspersed RNA.

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Synonyms and alternative names related to POU5F3.3

POU class 5 homeobox 3, gene 3 L homeolog (pou5f3.3.L), oct-60, oct60, pou5f1.3, XLPOU-60, XOct-60, xoct60

Protein level used designations for POU5F3.3

  • POU class 5 homeobox 1, gene 3
  • POU class V protein oct-60
  • POU domain, class 5, transcription factor 1.3
  • POU-domain protein
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