PON2 产品
(Paraoxonase 2 (PON2))
Categories
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured PON2 Categories
PON2 抗体
High quality antibodies with extensive validation data.
PON2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PON2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PON2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IP
Validations
- (7)
Cat. No.
ABIN7440995
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN2855759
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (4)
Cat. No.
ABIN651946
Quantity
400 μL
Datasheet
Datasheet
Recommended PON2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969140
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958392
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958393
Quantity
96 tests
Datasheet
Datasheet
Recommended PON2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315744
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397240
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407646
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PON2 Products
: "Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer." in: Cell death & disease, Vol. 9, Issue 3, pp. 392, (2019) (PubMed).: "Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone." in: The Journal of biological chemistry, Vol. 290, Issue 11, pp. 7247-58, (2015) (PubMed).
: "DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress." in: PLoS ONE, Vol. 9, Issue 9, pp. e106601, (2014) (PubMed).
: "Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis." in: Antioxidants & redox signaling, Vol. 14, Issue 3, pp. 341-51, (2011) (PubMed).
: "Paraoxonase gene polymorphism in south-western Korean population." in: Journal of Korean medical science, Vol. 24, Issue 4, pp. 561-6, (2009) (PubMed).
: "Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning." in: Toxicology, Vol. 233, Issue 1-3, pp. 47-59, (2007) (PubMed).
: "Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?" in: Free radical biology & medicine, Vol. 37, Issue 9, pp. 1317-23, (2004) (PubMed).
: "Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 21, Issue 4, pp. 542-7, (2001) (PubMed).
Synonyms and alternative names related to PON2
serum paraoxonase/arylesterase 2 (LOC100303695), paraoxonase 2 (PON2), paraoxonase 2 L homeolog (pon2.L), serum paraoxonase/arylesterase 2 (BDBG_00600), Serum paraoxonase/arylesterase 2 (pon2), paraoxonase 2 (Pon2), 6330405I24Rik, AI481612, MGC53915, pon1, PON2, pon2Protein level used designations for PON2
- A-esterase 2
- Aromatic esterase 2
- PON 2
- Serum aryldialkylphosphatase 2
- Serum paraoxonase/arylesterase 2
- paraoxonase 2
- celiac disease 2
- serum paraoxonase/arylesterase 2-like
- serum paraoxonase/arylesterase 2
- aromatic esterase 2
- paraoxonase nirs
- serum aryldialkylphosphatase 2
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- Potassium Channel KAT3
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- Potassium Channel, Subfamily K, Member 5
- Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2
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