POM121 产品
(POM121 Membrane Glycoprotein (POM121))
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The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and multiple pseudogenes have been identified. [provided by RefSeq, Mar 2012].
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POM121 抗体
High quality antibodies with extensive validation data.
Recommended POM121 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (5)
- (8)
Cat. No.
ABIN2855297
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7246724
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6264352
Quantity
100 μL
Datasheet
Datasheet
Recommended POM121 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6233749
Quantity
96 tests
Datasheet
Datasheet
Recommended POM121 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3117339
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our POM121 Products
: "Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 24, Issue 5, pp. 338-353, (2019) (PubMed).: "POM121 is identified as a novel prognostic marker of oral squamous cell carcinoma." in: Journal of Cancer, Vol. 10, Issue 19, pp. 4473-4480, (2019) (PubMed).
: "Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import. ..." in: Cell, Vol. 174, Issue 5, pp. 1200-1215.e20, (2019) (PubMed).
: "The transmembrane nucleoporin Pom121 ensures efficient HIV-1 pre-integration complex nuclear import." in: Virology, Vol. 521, pp. 169-174, (2018) (PubMed).
: "Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma." in: Frontiers in oncology, Vol. 8, pp. 465, (2018) (PubMed).
: "Proaggregant nuclear factor(s) trigger rapid formation of α-synuclein aggregates in apoptotic neurons." in: Acta neuropathologica, Vol. 132, Issue 1, pp. 77-91, (2017) (PubMed).
: "Analysis of the initiation of nuclear pore assembly by ectopically targeting nucleoporins to chromatin." in: Nucleus (Austin, Tex.), Vol. 6, Issue 1, pp. 40-54, (2015) (PubMed).
: "The SUMO proteases SENP1 and SENP2 play a critical role in nucleoporin homeostasis and nuclear pore complex function." in: Molecular biology of the cell, Vol. 25, Issue 1, pp. 160-8, (2014) (PubMed).
Synonyms and alternative names related to POM121
POM121 transmembrane nucleoporin (POM121), nuclear pore membrane protein 121 (Pom121), POM121 transmembrane nucleoporin (Pom121), POM121 transmembrane nucleoporin C-like (POM121CL), POM121 transmembrane nucleoporin C (POM121C), POM121 transmembrane nucleoporin (pom121), nuclear envelope pore membrane protein POM 121C (LOC100604279), POM121 membrane glycoprotein b (pom121-b), 2610027A18Rik, C80273, mKIAA0618, P145, POM121, POM121A, POM121C, wu:fa16c07, wu:fl35g12Protein level used designations for POM121
- POM121 membrane glycoprotein
- nuclear envelope pore membrane protein POM 121
- nuclear envelope pore membrane protein POM 121A
- nuclear pore membrane protein 121 kDa
- nucleoporin Nup121
- pore membrane protein of 121 kDa
- P145
- nuclear pore membrane glycoprotein 121 kD
- nuclear pore membrane protein 121
- POM121 membrane glycoprotein C
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