Poly A Binding Protein Nuclear 1 产品
(Poly A Binding Protein Nuclear 1 (PABPN1))
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This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010].
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Poly A Binding Protein Nuclear 1 抗体
High quality antibodies with extensive validation data.
Poly A Binding Protein Nuclear 1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Poly A Binding Protein Nuclear 1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IF, IHC
Validations
- (14)
Cat. No.
ABIN7075116
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC, FACS
Validations
- (5)
Cat. No.
ABIN7127661
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application
WB, ICC
Validations
- (1)
- (5)
Cat. No.
ABIN2778908
Quantity
100 μL
Datasheet
Datasheet
Recommended Poly A Binding Protein Nuclear 1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5853467
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Schizosaccharomyces pombe
Source
Yeast
Validations
Cat. No.
ABIN1510128
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Poly A Binding Protein Nuclear 1 Products
: "ALYREF mainly binds to the 5' and the 3' regions of the mRNA in vivo." in: Nucleic acids research, Vol. 45, Issue 16, pp. 9640-9653, (2017) (PubMed).: "[Arteriovenous neoadjuvant FLEOX chemotherapy with nutritional support improves the resectable rate for advanced gastric cancer]." in: Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, Vol. 11, Issue 5, pp. 428-31, (2008) (PubMed).
Synonyms and alternative names related to Poly A Binding Protein Nuclear 1
poly(A) binding protein nuclear 1 (PABPN1), poly(A) binding protein, nuclear 1 (Pabpn1), poly(A) binding protein 2 (PAB2), poly(A) binding protein, nuclear 1 S homeolog (pabpn1.S), poly(A) binding protein, nuclear 1 L homeolog (pabpn1.L), polyadenylate-binding protein 2 (LOC100728725), poly(A) binding protein Pab2 (pab2), poly(A) binding protein, nuclear 1 (pabpn1), ARABIDOPSIS POLY(A) BINDING 2, ATPAB2, F28A23.130, F28A23_130, fb19c03, mPABII, OPMD, opmd, PAB2, pab2, PABII, PABP-2, PABP2, pabp2, Pabp3, pabpii, pabpn1, Pabpn1, POLY(A)-BINDING PROTEIN 2, Poly(A)-binding protein 2, POLY(A) BINDING PROTEIN 2, poly(A) binding protein 2, wu:fb17e03, wu:fb18c06, wu:fb19c03, zgc:85979, zgc:92452Protein level used designations for Poly A Binding Protein Nuclear 1
- poly(A) binding protein 2
- poly(A) binding protein II
- polyadenylate-binding protein 2
- PABII
- PABP-2
- nuclear poly(A)-binding protein 1
- poly(A)-binding protein 2
- poly(A)-binding protein II
- polyadenylate-binding nuclear protein 1
- PABII-A
- PABP-2-A
- XLnPABP2-A
- nPABP2-A
- nuclear poly(A)-binding protein 1-A
- poly(A)-binding protein 2-A
- poly(A)-binding protein II-A
- polyadenylate-binding nuclear protein 1-A
- polyadenylate-binding protein 2-A
- xPABPII-A
- PABII-B
- PABP-2-B
- XLnPABP2-B
- nPABP2-B
- nuclear poly(A)-binding protein 1-B
- poly(A)-binding protein 2-B
- poly(A)-binding protein II-B
- polyadenylate-binding nuclear protein 1-B
- polyadenylate-binding protein 2-B
- xPABPII-B
- poly(A) binding protein, nuclear 1
- Poly(A)-binding protein II
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