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POLRMT 产品

(Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))

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This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008].

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Featured POLRMT Categories

POLRMT 抗体

High quality antibodies with extensive validation data.

POLRMT 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLRMT 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (4)
Cat. No. ABIN7269460
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, ICC, IHC (p), CUT&RUN
Validations
  • (3)
  • (3)
Cat. No. ABIN2856044
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN562313
Quantity 50 μL
Datasheet Datasheet

Recommended POLRMT 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315724
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315722
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our POLRMT Products

Kasinathan, Henikoff: "Non-B-Form DNA Is Enriched at Centromeres." in: Molecular biology and evolution, Vol. 35, Issue 4, pp. 949-962, (2019) (PubMed).

Thakur, Henikoff: "Unexpected conformational variations of the human centromeric chromatin complex." in: Genes & development, Vol. 32, Issue 1, pp. 20-25, (2018) (PubMed).

Sobek, Dalla Rosa, Pommier, Bornholz, Kalfalah, Zhang, Wiesner, von Kleist-Retzow, Hillebrand, Schaal, Mielke, Christensen, Boege: "Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I." in: Nucleic acids research, Vol. 41, Issue 21, pp. 9848-57, (2014) (PubMed).

Salem, Whitaker-Menezes, Howell, Sotgia, Lisanti: "Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 22, pp. 4174-80, (2012) (PubMed).

Sotgia, Whitaker-Menezes, Martinez-Outschoorn, Salem, Tsirigos, Lamb, Sneddon, Hulit, Howell, Lisanti: "Mitochondria "fuel" breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 23, pp. 4390-401, (2012) (PubMed).

Bogenhagen, Rousseau, Burke: "The layered structure of human mitochondrial DNA nucleoids." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).

Kravchenko, Rogozin, Koonin, Chumakov: "Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin." in: Nature, Vol. 436, Issue 7051, pp. 735-9, (2005) (PubMed).

Gaspari, Falkenberg, Larsson, Gustafsson: "The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells." in: The EMBO journal, Vol. 23, Issue 23, pp. 4606-14, (2004) (PubMed).

Tiranti, Savoia, Forti, DApolito, Centra, Rocchi, Zeviani: "Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database." in: Human molecular genetics, Vol. 6, Issue 4, pp. 615-25, (1997) (PubMed).

Synonyms and alternative names related to POLRMT

RNA polymerase mitochondrial (Polrmt), polymerase (RNA) mitochondrial (DNA directed) L homeolog (polrmt.L), polymerase (RNA) mitochondrial (DNA directed) (polrmt), RNA polymerase mitochondrial (POLRMT), polymerase (RNA) mitochondrial (DNA directed) (Polrmt), 1110018N15Rik, 4932416K13, APOLMT, h-mtRPOL, MTRNAP, mtRPO, MTRPOL, POLRMT, polrmt-a, si:dkeyp-74c5.5, wu:fb73g10

Protein level used designations for POLRMT

  • DNA-directed RNA polymerase, mitochondrial
  • polymerase (RNA) mitochondrial (DNA directed)
  • mitochondrial DNA-directed RNA polymerase
  • mtRPOL
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