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POLR3H 产品

(Polymerase (RNA) III (DNA Directed) Polypeptide H (22.9kD) (POLR3H))

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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNA. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa- B through the RIG-I pathway (By similarity).

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Featured POLR3H Categories

POLR3H 抗体

High quality antibodies with extensive validation data.

POLR3H 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLR3H 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7185433
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3186525
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, IF
Validations
  • (1)
Cat. No. ABIN6258482
Quantity 100 μL
Datasheet Datasheet

Recommended POLR3H 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124526
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315718
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131232
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our POLR3H Products

Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

Synonyms and alternative names related to POLR3H

polymerase (RNA) III (DNA directed) polypeptide H (Polr3h), RNA polymerase III subunit H (Polr3h), RNA polymerase III subunit H (POLR3H), 5031409G22Rik, RPC8, RPC22.9

Protein level used designations for POLR3H

  • DNA-directed RNA polymerase III subunit H
  • DNA-directed RNA polymerase III subunit RPC8
  • RNA polymerase III subunit C7
  • DNA-directed RNA polymerase III subunit 22.9 kDa polypeptide
  • RNA nucleotidyltransferase (DNA-directed)
  • RNA polymerase III subunit 22.9 kDa subunit
  • RNA polymerase III subunit C8
  • RNA polymerase III subunit RPC8
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