POLI 抗体
(Polymerase (DNA Directed) iota (POLI))
Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity (By similarity).
recommended
recommended
POLI 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
recommended
POLI 抗体 by 应用范围
Find POLI 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.
POLI 抗体 by 抗体来源
Find POLI 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
POLI 抗体 by 克隆形成能力
Find available monoclonal or polyclonal POLI 抗体. Click on a link to go to the corresponding products.
POLI 抗体 by 克隆
Find POLI 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular POLI 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
- (5)
Cat. No.
ABIN564869
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6264338
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7150251
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257132
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1491524
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN1682214
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
- (1)
Cat. No.
ABIN1714435
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7184828
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6744961
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
Application
WB
Validations
- (2)
Cat. No.
ABIN2784869
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN5531016
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1700933
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN2812442
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1693665
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
IF (cc), IF (p)
Validations
Cat. No.
ABIN1695485
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our POLI 抗体
: "DNA polymerase ι is acetylated in response to SN2 alkylating agents." in: Scientific reports, Vol. 9, Issue 1, pp. 4789, (2019) (PubMed).: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).
: "Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication." in: Molecular and cellular biology, Vol. 35, Issue 4, pp. 699-715, (2015) (PubMed).
: "Identification of novel DNA-damage tolerance genes reveals regulation of translesion DNA synthesis by nucleophosmin." in: Nature communications, Vol. 5, pp. 5437, (2014) (PubMed).
: "DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity." in: Nucleic acids research, Vol. 40, Issue 1, pp. 170-80, (2011) (PubMed).
: "Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation." in: Journal of nucleic acids, Vol. 2010, pp. 750296, (2010) (PubMed).
: "DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 28, pp. 11552-7, (2009) (PubMed).
: "Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations." in: Cancer research, Vol. 67, Issue 7, pp. 3018-26, (2007) (PubMed).
: "The role of DNA polymerase iota in UV mutational spectra." in: Mutation research, Vol. 599, Issue 1-2, pp. 58-65, (2006) (PubMed).
: "Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template." in: The EMBO journal, Vol. 20, Issue 11, pp. 2914-22, (2001) (PubMed).
Aliases for POLI 抗体
DNA polymerase iota (POLI) 抗体polymerase (DNA directed) iota (poli) 抗体
DNA polymerase iota (LOC551219) 抗体
DNA polymerase iota (AFUA_4G11140) 抗体
DNA polymerase iota (LOC5568276) 抗体
polymerase (DNA directed) iota (Pol-iota) 抗体
polymerase (DNA directed), iota (Poli) 抗体
DNA polymerase iota (Poli) 抗体
GB12093 抗体
NV16187 抗体
poli 抗体
RAD3OB 抗体
RAD30B 抗体
Rad30b 抗体
wu:fc27h11 抗体
zgc:110185 抗体
您还需要查找其他产品吗？
You are here:
