POLH 抗体
(Polymerase (DNA Directed), eta (POLH))
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA\; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq, Jul 2008].
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POLH 抗体 by 适用
Find POLH 抗体 for a variety of species such as anti-Human POLH, anti-Mouse POLH, anti-Rat POLH. The species listed below are among those available. Click on a link to go to the corresponding products.
POLH 抗体 by 应用范围
Find POLH 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.
POLH 抗体 by 抗体来源
Find POLH 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
POLH 抗体 by 抗原表位
Find POLH 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
POLH 抗体 by 克隆形成能力
Find available monoclonal or polyclonal POLH 抗体. Click on a link to go to the corresponding products.
POLH 抗体 by 克隆
Find POLH 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
Popular POLH 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7150247
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7252888
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN7259837
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN3022621
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN948279
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN519025
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6264337
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB
Validations
- (2)
Cat. No.
ABIN3042492
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IC
Validations
- (2)
Cat. No.
ABIN7308184
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC
Validations
Cat. No.
ABIN1713764
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN1700262
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1694810
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1692995
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN1698449
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF (p), IF (cc)
Validations
Cat. No.
ABIN5001353
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our POLH 抗体
: "c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks." in: Molecular biology of the cell, Vol. 23, Issue 10, pp. 1943-54, (2012) (PubMed).: "Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication." in: The Journal of cell biology, Vol. 191, Issue 5, pp. 953-66, (2010) (PubMed).
: "Contributions of ubiquitin- and PCNA-binding domains to the activity of Polymerase eta in Saccharomyces cerevisiae." in: Nucleic acids research, Vol. 35, Issue 3, pp. 881-9, (2007) (PubMed).
: "Polymerase eta is a short-lived, proteasomally degraded protein that is temporarily stabilized following UV irradiation in Saccharomyces cerevisiae." in: Journal of molecular biology, Vol. 366, Issue 4, pp. 1074-86, (2007) (PubMed).
: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).
: "Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions." in: The EMBO journal, Vol. 20, Issue 24, pp. 7303-12, (2001) (PubMed).
: "Genomic structure, chromosomal localization and identification of mutations in the xeroderma pigmentosum variant (XPV) gene." in: Oncogene, Vol. 19, Issue 41, pp. 4721-8, (2000) (PubMed).
: "The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta." in: Nature, Vol. 399, Issue 6737, pp. 700-4, (1999) (PubMed).
: "hRAD30 mutations in the variant form of xeroderma pigmentosum." in: Science (New York, N.Y.), Vol. 285, Issue 5425, pp. 263-5, (1999) (PubMed).
Aliases for POLH 抗体
polymerase (DNA directed), eta S homeolog (polh.S) 抗体DNA polymerase eta (POLH) 抗体
polymerase (DNA directed), eta (polh) 抗体
DNA polymerase eta (Tb10.70.6190) 抗体
putative DNA polymerase eta (LINJ_21_0690) 抗体
polymerase (DNA directed), eta (Polh) 抗体
DNA polymerase eta (LOC100443019) 抗体
DNA polymerase eta (polh) 抗体
DNA polymerase eta (Polh) 抗体
polymerase (DNA directed), eta (RAD 30 related) (Polh) 抗体
fc50a12 抗体
POLH 抗体
RAD30 抗体
RAD30A 抗体
wu:fc50a12 抗体
XP-V 抗体
XPV 抗体
zgc:136881 抗体
zgc:152642 抗体
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