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POLG2 产品

(Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

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This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009].

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Featured POLG2 Categories

POLG2 抗体

High quality antibodies with extensive validation data.

POLG2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLG2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB, IF
Validations
  • (6)
Cat. No. ABIN6145894
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7262585
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN6243952
Quantity 400 μL
Datasheet Datasheet

Recommended POLG2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6231872
Quantity 96 tests
Datasheet Datasheet

Recommended POLG2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315644
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711899
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729307
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our POLG2 Products

Haba, Hatakeyama, Kinoshita, Teramae, Azma, Hatano, Matsuda: "The modulation of vascular ATP-sensitive K+ channel function via the phosphatidylinositol 3-kinase-Akt pathway activated by phenylephrine." in: The Journal of pharmacology and experimental therapeutics, Vol. 334, Issue 2, pp. 673-8, (2010) (PubMed).

Longley, Clark, Yu Wai Man, Hudson, Durham, Taylor, Nightingale, Turnbull, Copeland, Chinnery: "Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia." in: American journal of human genetics, Vol. 78, Issue 6, pp. 1026-34, (2006) (PubMed).

Synonyms and alternative names related to POLG2

DNA polymerase gamma 2, accessory subunit (Polg2), DNA polymerase gamma 2, accessory subunit (POLG2), polymerase (DNA directed), gamma 2, accessory subunit (polg2), polymerase (DNA directed), gamma 2, accessory subunit (Polg2), polymerase (DNA directed), gamma 2, accessory subunit L homeolog (polg2.L), HP55, im:7158733, MTPOLB, mtpolb, PEOA4, POLB, POLG-BETA, POLG2, POLGB, si:ch211-157f15.3

Protein level used designations for POLG2

  • DNA polymerase subunit gamma-2, mitochondrial
  • polymerase (DNA directed), gamma 2, accessory subunit
  • DNA polymerase subunit gamma-2, mitochondrial-like
  • DNA polymerase gamma accessory 55 kDa subunit
  • mitochondrial DNA polymerase accessory subunit
  • mitochondrial DNA polymerase subunit gamma-2
  • mitochondrial DNA polymerase, accessory subunit
  • p55
  • mitochondrial polymerase gamma 2
  • mtPolB
  • polG-beta
  • polymerase, gamma 2
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