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POLD2 产品

(Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

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This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012].

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Featured POLD2 Categories

POLD2 抗体

High quality antibodies with extensive validation data.

POLD2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7253536
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN519021
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN519020
Quantity 50 μg
Datasheet Datasheet

Recommended POLD2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6235139
Quantity 96 tests
Datasheet Datasheet

Recommended POLD2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315626
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7318412
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1692161
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our POLD2 Products

Tsurimoto, Shinozaki, Yano, Seki, Enomoto: "Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 10, Issue 1, pp. 13-22, (2005) (PubMed).

He, Tan, Downey, So: "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 21, pp. 11979-84, (2001) (PubMed).

Perez, Leon, Lee: "Characterization of the 5'-flanking region of the gene encoding the 50 kDa subunit of human DNA polymerase delta." in: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 231-6, (2000) (PubMed).

Zhang, Tan, McMullen, Downey, So: "Cloning of the cDNAs for the small subunits of bovine and human DNA polymerase delta and chromosomal location of the human gene (POLD2)." in: Genomics, Vol. 29, Issue 1, pp. 179-86, (1996) (PubMed).

Synonyms and alternative names related to POLD2

DNA polymerase delta 2, accessory subunit (POLD2), polymerase (DNA directed), delta 2, regulatory subunit (Pold2), DNA polymerase delta 2, accessory subunit (Pold2), polymerase (DNA directed), delta 2, accessory subunit L homeolog (pold2.L), polymerase (DNA directed), delta 2, regulatory subunit (pold2), 50kDa, cdc1, p50, po1D2, si:dz150f13.3, zgc:55633, zgc:77043

Protein level used designations for POLD2

  • DNA polymerase delta subunit 2
  • DNA polymerase delta subunit p50
  • Pol delta B subunit (p50)
  • polymerase (DNA directed), delta 2, regulatory subunit 50kDa
  • DNA-directed DNA polymerase delta 2
  • polymerase (DNA directed), delta 2, regulatory subunit
  • xlCdc1
  • DAN polymerase delta 2, accessory subunit
  • polymerase (DNA directed), delta 2, accessory subunit
  • polymerase (DNA) delta 2, accessory subunit
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