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POLD1 产品

(Polymerase (DNA Directed), delta 1, Catalytic Subunit 125kDa (POLD1))
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012].

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Featured POLD1 Categories

POLD1 抗体

High quality antibodies with extensive validation data.

POLD1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

POLD1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, IF
Validations
  • (4)
Cat. No. ABIN7010566
Quantity 60 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (4)
Cat. No. ABIN2855506
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC
Validations
  • (3)
Cat. No. ABIN7150227
Quantity 100 μg
Datasheet Datasheet

Recommended POLD1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958687
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5657980
Quantity 96 tests
Datasheet Datasheet

Recommended POLD1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315624
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422910
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418974
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our POLD1 Products

Xiang, Laurent, Hsu, Nachtergaele, Lu, Sheng, Xu, Chen, Ouyang, Wang, Ling, Hsu, Zou, Jambhekar, He, Shi: "RNA m6A methylation regulates the ultraviolet-induced DNA damage response." in: Nature, Vol. 543, Issue 7646, pp. 573-576, (2017) (PubMed).

Kundu, Balusu, Jaiswal, Narayan: "Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: implication of base excision repair pathways." in: Carcinogenesis, Vol. 28, Issue 10, pp. 2089-95, (2007) (PubMed).

Saitoh, Pizzi, Wang: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).

Liu, Mo, Rodriguez-Belmonte, Lee: "Identification of a fourth subunit of mammalian DNA polymerase delta." in: The Journal of biological chemistry, Vol. 275, Issue 25, pp. 18739-44, (2000) (PubMed).

Wu, Zhang, Zeng, Zhang, Mo, Li, Lee: "Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins." in: The Journal of biological chemistry, Vol. 273, Issue 16, pp. 9561-9, (1998) (PubMed).

Sun, Jiang, Zhang, Zhang, Zhou, Li, Toomey, Lee: "Expression and characterization of the small subunit of human DNA polymerase delta." in: The Journal of biological chemistry, Vol. 272, Issue 20, pp. 13013-8, (1997) (PubMed).

Zeng, Jiang, Zhang, Hao, Lee: "DNA polymerase delta is involved in the cellular response to UV damage in human cells." in: The Journal of biological chemistry, Vol. 269, Issue 19, pp. 13748-51, (1994) (PubMed).

Yang, Chang, Zhang, Hao, Zhu, Toomey, Lee: "Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta." in: Nucleic acids research, Vol. 20, Issue 4, pp. 735-45, (1992) (PubMed).

Synonyms and alternative names related to POLD1

DNA polymerase delta 1, catalytic subunit (POLD1), DNA-polymerase-delta (DNApol-delta), polymerase (DNA directed), delta 1, catalytic subunit (pold1), DNA polymerase delta catalytic subunit (LOC100456571), polymerase (DNA directed), delta 1, catalytic subunit (Pold1), DNA polymerase delta 1, catalytic subunit (Pold1), DNA polymerase delta (POLD1), 125kDa, 5949, CAA61369, CDC2, cdc2, CG5949, CRCS10, Dmel\\CG5949, Dm Poldelta, DNA Pol Delta, dnapol delta, fla, im:7139126, l(3)72Ac, POLD, pold, Poldelta, Pol delta, zgc:152688

Protein level used designations for POLD1

  • CDC2 homolog
  • DNA polymerase delta catalytic subunit
  • DNA polymerase subunit delta p125
  • polymerase (DNA directed), delta 1, catalytic subunit 125kDa
  • CG5949-PA
  • DNA polymerase delta
  • DNA polymerase-delta
  • DNApol-delta-PA
  • lethal (3) 72Ac
  • DNA-directed DNA polymerase delta 1
  • DNA polymerase delta catalytic subunit-like
  • DNA polymerase delta 1, catalytic domain
  • DNA polymerase delta, catalytic subunit
  • DNA-dependent DNA polymerase
  • DAN polymerase delta 1, catalytic subunit
  • polymerase (DNA directed), delta 1, catalytic subunit
  • DNA polymerase delta1 catalytic subunit
  • flat head
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