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Podocin 产品

(Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))

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This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].

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Featured Podocin Categories

Podocin 抗体

High quality antibodies with extensive validation data.

Podocin 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Podocin 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7342489
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (2)
Cat. No. ABIN7432922
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (1)
Cat. No. ABIN7437470
Quantity 100 μL
Datasheet Datasheet

Recommended Podocin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7282506
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7288953
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392791
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Podocin Products

Zhao, Li, Wang, Liu: "Alteration of Connexin43 expression in a rat model of obesity-related glomerulopathy." in: Experimental and molecular pathology, Vol. 104, Issue 1, pp. 12-18, (2018) (PubMed).

Chen, Chen, Liu, Ma: "Effect of simvastatin on the expression of nephrin, podocin, and vascular endothelial growth factor (VEGF) in podocytes of diabetic rat." in: International journal of clinical and experimental medicine, Vol. 8, Issue 10, pp. 18225-34, (2016) (PubMed).

Ishida, Kami, Kusaba, Kirita, Kishida, Mazda, Adachi, Gojo: "Kidney-specific Sonoporation-mediated Gene Transfer." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 1, pp. 125-34, (2016) (PubMed).

Jayachandran, Lugo, Heiling, Miller, Rule, Lieske: "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." in: Biology of sex differences, Vol. 6, pp. 2, (2015) (PubMed).

Carlos, Sonehara, Oliani, Burdmann: "Predictive usefulness of urinary biomarkers for the identification of cyclosporine A-induced nephrotoxicity in a rat model." in: PLoS ONE, Vol. 9, Issue 7, pp. e103660, (2015) (PubMed).

Zhang, Guo, Song, Zhou: "Vitamin D prevents podocyte injury via regulation of macrophage M1/M2 phenotype in diabetic nephropathy rats." in: Endocrinology, Vol. 155, Issue 12, pp. 4939-50, (2014) (PubMed).

Simon, Lemoine, Fonbonne, Jaffuel, Léonard, Gautier, Pasquier, Salvador: "Absolute quantification of podocin, a potential biomarker of glomerular injury in human urine, by liquid chromatography-multiple reaction monitoring cubed mass spectrometry." in: Journal of pharmaceutical and biomedical analysis, Vol. 94, pp. 84-91, (2014) (PubMed).

Hao, Pan, Zheng, Wang: "Effect of Cordyceps sinensis and Tripterygium wilfordii polyglycosidium on podocytes in rats with diabetic nephropathy." in: Experimental and therapeutic medicine, Vol. 7, Issue 6, pp. 1465-1470, (2014) (PubMed).

Qu, Du, Zhang, Li, Han, Qiu: "Changes in the expression of bone morphogenetic protein 7 and tamm- horsfall protein in the early stages of diabetic nephropathy." in: Nephro-urology monthly, Vol. 4, Issue 2, pp. 466-9, (2013) (PubMed).

Relle, Cash, Brochhausen, Strand, Menke, Galle, Schwarting: "New perspectives on the renal slit diaphragm protein podocin." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 24, Issue 8, pp. 1101-10, (2011) (PubMed).

Synonyms and alternative names related to Podocin

nephrosis 2, podocin (Nphs2), NPHS2, podocin (NPHS2), NPHS2, podocin (Nphs2), AI790225, PDCN, podocin, SRN1

Protein level used designations for Podocin

  • nephrosis 2 homolog, podocin
  • podocin
  • nephrosis 2 idiopathic steroid-resistant (podocin)
  • nephrosis 2, idiopathic, steroid-resistant (podocin)
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