Podocin 产品
(Nephrosis 2, Idiopathic, Steroid-Resistant (Podocin) (NPHS2))
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This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
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Featured Podocin Categories
Podocin 抗体
High quality antibodies with extensive validation data.
Podocin 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Podocin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7101468
Quantity
20 μL
Datasheet
Datasheet
Recommended Podocin 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7392791
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7496890
Quantity
200 μg
Datasheet
Datasheet
Latest Publications for our Podocin Products
: "Alteration of Connexin43 expression in a rat model of obesity-related glomerulopathy." in: Experimental and molecular pathology, Vol. 104, Issue 1, pp. 12-18, (2018) (PubMed).: "Effect of simvastatin on the expression of nephrin, podocin, and vascular endothelial growth factor (VEGF) in podocytes of diabetic rat." in: International journal of clinical and experimental medicine, Vol. 8, Issue 10, pp. 18225-34, (2016) (PubMed).
: "Kidney-specific Sonoporation-mediated Gene Transfer." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 1, pp. 125-34, (2016) (PubMed).
: "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." in: Biology of sex differences, Vol. 6, pp. 2, (2015) (PubMed).
: "Predictive usefulness of urinary biomarkers for the identification of cyclosporine A-induced nephrotoxicity in a rat model." in: PLoS ONE, Vol. 9, Issue 7, pp. e103660, (2015) (PubMed).
: "Vitamin D prevents podocyte injury via regulation of macrophage M1/M2 phenotype in diabetic nephropathy rats." in: Endocrinology, Vol. 155, Issue 12, pp. 4939-50, (2014) (PubMed).
: "Absolute quantification of podocin, a potential biomarker of glomerular injury in human urine, by liquid chromatography-multiple reaction monitoring cubed mass spectrometry." in: Journal of pharmaceutical and biomedical analysis, Vol. 94, pp. 84-91, (2014) (PubMed).
: "Effect of Cordyceps sinensis and Tripterygium wilfordii polyglycosidium on podocytes in rats with diabetic nephropathy." in: Experimental and therapeutic medicine, Vol. 7, Issue 6, pp. 1465-1470, (2014) (PubMed).
: "Changes in the expression of bone morphogenetic protein 7 and tamm- horsfall protein in the early stages of diabetic nephropathy." in: Nephro-urology monthly, Vol. 4, Issue 2, pp. 466-9, (2013) (PubMed).
: "New perspectives on the renal slit diaphragm protein podocin." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 24, Issue 8, pp. 1101-10, (2011) (PubMed).
Synonyms and alternative names related to Podocin
nephrosis 2, podocin (Nphs2), NPHS2, podocin (NPHS2), NPHS2, podocin (Nphs2), AI790225, PDCN, podocin, SRN1Protein level used designations for Podocin
- nephrosis 2 homolog, podocin
- podocin
- nephrosis 2 idiopathic steroid-resistant (podocin)
- nephrosis 2, idiopathic, steroid-resistant (podocin)
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