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Purine Nucleoside Phosphorylase 产品

(Purine Nucleoside Phosphorylase (PNP))
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008].

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Featured Purine Nucleoside Phosphorylase Categories

Purine Nucleoside Phosphorylase 抗体

High quality antibodies with extensive validation data.

Purine Nucleoside Phosphorylase ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Purine Nucleoside Phosphorylase 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Purine Nucleoside Phosphorylase 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IHC (p)
Validations
  • (6)
Cat. No. ABIN5647213
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN4886701
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN948191
Quantity 100 μg
Datasheet Datasheet

Recommended Purine Nucleoside Phosphorylase ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative
Validations
Cat. No. ABIN1057927
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method Quantitative
Validations
Cat. No. ABIN1057928
Quantity 96 tests
Datasheet Datasheet
Reactivity Rabbit
Analytical Method Quantitative
Validations
Cat. No. ABIN1057929
Quantity 96 tests
Datasheet Datasheet

Recommended Purine Nucleoside Phosphorylase 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419154
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419160
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419157
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Purine Nucleoside Phosphorylase Products

Zhao, Zhang, Luo, Wang, Zhou, Zhong, Xie, Jiang, Yang, Tang, Pan, Hall, Luong, Fan, Varghese, Moorhead, Pinzani, Chen, Ruan: "CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis." in: Journal of hepatology, Vol. 69, Issue 3, pp. 705-717, (2018) (PubMed).

Kojima, Chiyomaru, Kawakami, Yoshino, Enokida, Nohata, Fuse, Ichikawa, Naya, Nakagawa, Seki: "Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer." in: British journal of cancer, Vol. 106, Issue 2, pp. 405-13, (2012) (PubMed).

Synonyms and alternative names related to Purine Nucleoside Phosphorylase

purine nucleoside phosphorylase (PNP), purine nucleoside phosphorylase (Pnp), purine-nucleoside phosphorylase (Pnp), AL024301, AU015798, NP, Np, Np-1, Np-2, Pnp1, PRO1837, PUNP

Protein level used designations for Purine Nucleoside Phosphorylase

  • inosine phosphorylase
  • inosine-guanosine phosphorylase
  • purine-nucleoside:orthophosphate ribosyltransferase
  • nucleoside phosphorylase
  • purine nucleoside phosphorylase
  • purine-nucleoside phosphorylase 1
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