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PNPLA2 产品

(Patatin-Like phospholipase Domain Containing 2 (PNPLA2))

Categories

This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. [provided by RefSeq, Jul 2010].

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Featured PNPLA2 Categories

PNPLA2 抗体

High quality antibodies with extensive validation data.

PNPLA2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PNPLA2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PNPLA2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7162692
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN566087
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7162696
Quantity 100 μL
Datasheet Datasheet

Recommended PNPLA2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975754
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962706
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6963150
Quantity 96 tests
Datasheet Datasheet

Recommended PNPLA2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1315583
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315585
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409170
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PNPLA2 Products

Alipoor, Esmaillzadeh, Mahdavi-Mazdeh, Yaseri, Zahed, Hosseinzadeh-Attar: "The relationship of serum adipokines with malnutrition inflammation score in haemodialysis." in: European journal of clinical investigation, Vol. 47, Issue 8, pp. 545-554, (2018) (PubMed).

Hu, Cui, Liu, Wang: "Emodin and rhein decrease levels of hypoxia-inducible factor-1α in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells." in: Oncotarget, Vol. 8, Issue 50, pp. 88008-88020, (2017) (PubMed).

Kamikubo, Kai, Tsuji-Naito, Akagawa: "β-Caryophyllene attenuates palmitate-induced lipid accumulation through AMPK signaling by activating CB2 receptor in human HepG2 hepatocytes." in: Molecular nutrition & food research, Vol. 60, Issue 10, pp. 2228-2242, (2017) (PubMed).

Windschüttl, Kampfer, Mayer, Flenkenthaler, Fröhlich, Schwarzer, Köhn, Urbanski, Arnold, Mayerhofer: "Human testicular peritubular cells secrete pigment epithelium-derived factor (PEDF), which may be responsible for the avascularity of the seminiferous tubules." in: Scientific reports, Vol. 5, pp. 12820, (2015) (PubMed).

Mason, Meex, Russell, Canny, Watt: "Cellular localization and associations of the major lipolytic proteins in human skeletal muscle at rest and during exercise." in: PLoS ONE, Vol. 9, Issue 7, pp. e103062, (2014) (PubMed).

He, Wu, Gong, Luo, Zhang, Li, Lu, Wei, Yang: "Enhanced efficacy of combination therapy with adeno‑associated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma." in: Molecular medicine reports, Vol. 9, Issue 6, pp. 2069-76, (2014) (PubMed).

Tavian, Missaglia, Redaelli, Pennisi, Invernici, Wessalowski, Maiwald, Arca, Coleman: "Contribution of novel ATGL missense mutations to the clinical phenotype of NLSD-M: a strikingly low amount of lipase activity may preserve cardiac function." in: Human molecular genetics, Vol. 21, Issue 24, pp. 5318-28, (2012) (PubMed).

Steinberg, Kemp, Watt: "Adipocyte triglyceride lipase expression in human obesity." in: American journal of physiology. Endocrinology and metabolism, Vol. 293, Issue 4, pp. E958-64, (2007) (PubMed).

Smirnova, Goldberg, Makarova, Lin, Brown, Jackson: "ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells." in: EMBO reports, Vol. 7, Issue 1, pp. 106-13, (2006) (PubMed).

Schoenborn, Heid, Vollmert, Lingenhel, Adams, Hopkins, Illig, Zimmermann, Zechner, Hunt, Kronenberg: "The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes." in: Diabetes, Vol. 55, Issue 5, pp. 1270-5, (2006) (PubMed).

Synonyms and alternative names related to PNPLA2

patatin like phospholipase domain containing 2 (PNPLA2), patatin like phospholipase domain containing 2 (pnpla2), patatin-like phospholipase domain containing 2 (Pnpla2), 0610039C21Rik, 1110001C14Rik, ATGL, Atgl, iPLA2zeta, PEDF-R, PNPLA2, pnpla2, RGD1309044, TTS-2.2, TTS2

Protein level used designations for PNPLA2

  • IPLA2-zeta
  • TTS2.2
  • adipose triglyceride lipase
  • calcium-independent phospholipase A2
  • desnutrin
  • patatin-like phospholipase domain containing protein 2
  • patatin-like phospholipase domain-containing protein 2
  • pigment epithelium-derived factor
  • transport-secretion protein 2.2
  • triglyceride hydrolase
  • patatin-like phospholipase domain containing 2
  • transport-secretion protein
  • PNPLA2/ATGL
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