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PNP 产品

(Nucleoside Phosphorylase (NP))
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008].

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Featured PNP Categories

PNP 抗体

High quality antibodies with extensive validation data.

PNP ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PNP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PNP 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IHC (p)
Validations
  • (6)
Cat. No. ABIN5647213
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN4886701
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN948191
Quantity 100 μg
Datasheet Datasheet

Recommended PNP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow
Analytical Method Quantitative
Validations
Cat. No. ABIN1057921
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method Quantitative
Validations
Cat. No. ABIN1057922
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method Quantitative
Validations
Cat. No. ABIN1057923
Quantity 96 tests
Datasheet Datasheet

Recommended PNP 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419154
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419160
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419157
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PNP Products

Zhao, Zhang, Luo, Wang, Zhou, Zhong, Xie, Jiang, Yang, Tang, Pan, Hall, Luong, Fan, Varghese, Moorhead, Pinzani, Chen, Ruan: "CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis." in: Journal of hepatology, Vol. 69, Issue 3, pp. 705-717, (2018) (PubMed).

Kojima, Chiyomaru, Kawakami, Yoshino, Enokida, Nohata, Fuse, Ichikawa, Naya, Nakagawa, Seki: "Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer." in: British journal of cancer, Vol. 106, Issue 2, pp. 405-13, (2012) (PubMed).

Synonyms and alternative names related to PNP

purine nucleoside phosphorylase (PNP), purine nucleoside phosphorylase (Pnp), purine-nucleoside phosphorylase (Pnp), AL024301, AU015798, NP, Np, Np-1, Np-2, Pnp1, PRO1837, PUNP

Protein level used designations for PNP

  • inosine phosphorylase
  • inosine-guanosine phosphorylase
  • purine-nucleoside:orthophosphate ribosyltransferase
  • nucleoside phosphorylase
  • purine nucleoside phosphorylase
  • purine-nucleoside phosphorylase 1
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