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PLOD1 产品

(Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008].

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Featured PLOD1 Categories

PLOD1 抗体

High quality antibodies with extensive validation data.

PLOD1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PLOD1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PLOD1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
  • (7)
Cat. No. ABIN656585
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7441145
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN954205
Quantity 0.4 mL
Datasheet Datasheet

Recommended PLOD1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958786
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1773428
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774652
Quantity 96 tests
Datasheet Datasheet

Recommended PLOD1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315447
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315445
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7406872
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PLOD1 Products

Jover, Silvente, Marín, Martínez-González, Orriols, Martinez, Puche, Valdés, Rodriguez, Hernández-Romero: "Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 8, pp. 4459-4469, (2019) (PubMed).

Lindert, Cabral, Ausavarat, Tongkobpetch, Ludin, Barnes, Yeetong, Weis, Krabichler, Srichomthong, Makareeva, Janecke, Leikin, Röthlisberger, Rohrbach, Kennerknecht, Eyre, Suphapeetiporn, Giunta et al.: "MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta. ..." in: Nature communications, Vol. 7, pp. 11920, (2018) (PubMed).

Heard, Besio, Weis, Rai, Hudson, Dimori, Zimmerman, Kamykowski, Hogue, Swain, Burdine, Mackintosh, Tackett, Suva, Eyre, Morello: "Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation." in: PLoS genetics, Vol. 12, Issue 4, pp. e1006002, (2016) (PubMed).

Cabral, Ishikawa, Garten, Makareeva, Sargent, Weis, Barnes, Webb, Shaw, Ala-Kokko, Lacbawan, Högler, Leikin, Blank, Zimmerberg, Eyre, Yamada, Marini: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).

Wågsäter, Paloschi, Hanemaaijer, Hultenby, Bank, Franco-Cereceda, Lindeman, Eriksson: "Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve." in: Journal of the American Heart Association, Vol. 2, Issue 1, pp. e000034, (2013) (PubMed).

Synonyms and alternative names related to PLOD1

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (Plod1), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1), procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (Plod1), procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (PLOD3), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog (plod1.L), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a (plod1a), 2410042F05Rik, AI854890, AV007929, EDS6, ik:tdsubs_rzpd609-29b19, LH, LH1, Lh1, LLH, PLOD, Plod, plod, plod1, procollagen-lysine, wu:fc29c10, wu:fc95g08, wu:fi18a05, zgc:152876

Protein level used designations for PLOD1

  • lysine hydroxylase
  • lysyl hydroxlase 1
  • procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  • LH1
  • lysyl hydroxylase 1
  • procollagen-lysine 2-oxoglutarate 5-dioxygenase (lysine hydroxylase Ehlers-Danlos syndrome type VI)
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI)
  • 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine 5-dioxygenase
  • procollagen-lysine 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog
  • fc95g08
  • fi18a05
  • lh1
  • procollagen lysine 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a
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