PLOD1 产品
(Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
Categories
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008].
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Featured PLOD1 Categories
PLOD1 抗体
High quality antibodies with extensive validation data.
PLOD1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PLOD1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PLOD1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
- (7)
Cat. No.
ABIN656585
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7441145
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p), EIA
Validations
- (3)
Cat. No.
ABIN954205
Quantity
0.4 mL
Datasheet
Datasheet
Recommended PLOD1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958786
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1773428
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774652
Quantity
96 tests
Datasheet
Datasheet
Recommended PLOD1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315447
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1315445
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7406872
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PLOD1 Products
: "Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 8, pp. 4459-4469, (2019) (PubMed).: "MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta. ..." in: Nature communications, Vol. 7, pp. 11920, (2018) (PubMed).
: "Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation." in: PLoS genetics, Vol. 12, Issue 4, pp. e1006002, (2016) (PubMed).
: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." in: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).
: "Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve." in: Journal of the American Heart Association, Vol. 2, Issue 1, pp. e000034, (2013) (PubMed).
Synonyms and alternative names related to PLOD1
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (Plod1), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1), procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (Plod1), procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (PLOD3), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog (plod1.L), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a (plod1a), 2410042F05Rik, AI854890, AV007929, EDS6, ik:tdsubs_rzpd609-29b19, LH, LH1, Lh1, LLH, PLOD, Plod, plod, plod1, procollagen-lysine, wu:fc29c10, wu:fc95g08, wu:fi18a05, zgc:152876Protein level used designations for PLOD1
- lysine hydroxylase
- lysyl hydroxlase 1
- procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
- procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
- LH1
- lysyl hydroxylase 1
- procollagen-lysine 2-oxoglutarate 5-dioxygenase (lysine hydroxylase Ehlers-Danlos syndrome type VI)
- procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI)
- 2-oxoglutarate 5-dioxygenase 1
- procollagen-lysine 5-dioxygenase
- procollagen-lysine 2-oxoglutarate 5-dioxygenase 1
- procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog
- fc95g08
- fi18a05
- lh1
- procollagen lysine 2-oxoglutarate 5-dioxygenase 1
- procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a
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