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PLAUR 抗体

(Plasminogen Activator, Urokinase Receptor (PLAUR))
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008].
PLAUR 抗体  (AA 13-114) PLAUR 抗体  (AA 13-114) PLAUR 抗体 (AA 13-114) (ABIN7431179)

PLAUR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PLAUR 抗体  (AA 201-300) PLAUR 抗体  (AA 201-300) PLAUR 抗体 (AA 201-300) (ABIN675443)

PLAUR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated

PLAUR 抗体  (AA 23-305) PLAUR 抗体  (AA 23-305) PLAUR 抗体 (AA 23-305) (ABIN7193215)

PLAUR 适用: 人 WB, IHC, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 1D1B11 unconjugated

PLAUR 抗体 by Grade

Find PLAUR 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PLAUR 抗体 by 适用

Find PLAUR 抗体 for a variety of species such as anti-Human PLAUR, anti-Rat PLAUR, anti-Mouse PLAUR. The species listed below are among those available. Click on a link to go to the corresponding products.

PLAUR 抗体 by 应用范围

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PLAUR 抗体 by 抗体来源

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PLAUR 抗体 by 抗原表位

Find PLAUR 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PLAUR 抗体 by 克隆形成能力

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PLAUR 抗体 by 克隆

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PLAUR 抗体 by 标记

Find PLAUR 抗体 with a specific conjugate such as Biotin, FITC, PE. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PLAUR 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7431179
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc)
Validations
  • (5)
Cat. No. ABIN675443
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, ICC, FACS, Neut
Validations
  • (4)
Cat. No. ABIN7193215
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7175125
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (3)
Cat. No. ABIN7234357
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN2854760
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7437968
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN2565788
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN2565787
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (2)
Cat. No. ABIN4888508
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN652429
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7427957
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7431182
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7179103
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (1)
Cat. No. ABIN4888507
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our PLAUR 抗体

Wei, Li, Adair, Zhu, Cai, Merchant, Samelko, Liao, Koh, Tardi, Dande, Liu, Ma, Dibartolo, Hägele, Peev, Hayek, Cimbaluk, Tracy, Klein, Sever, Shattil, Arnaout, Reiser: "uPAR isoform 2 forms a dimer and induces severe kidney disease in mice." in: The Journal of clinical investigation, Vol. 130, (2019) (PubMed).

Hahm, Wei, Fernandez, Li, Tardi, Tracy, Wadhwani, Cao, Peev, Zloza, Lusciks, Hayek, OConnor, Bitzer, Gupta, Sever, Sykes, Scadden, Reiser: "Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease." in: Nature medicine, Vol. 23, Issue 1, pp. 100-106, (2017) (PubMed).

Magnussen, Hadler-Olsen, Costea, Berg, Jacobsen, Mortensen, Salo, Martinez-Zubiaurre, Winberg, Uhlin-Hansen, Svineng: "Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion." in: BMC cancer, Vol. 17, Issue 1, pp. 350, (2017) (PubMed).

Merino, Diaz, Jeanneret, Wu, Torre, Cheng, Yepes: "Urokinase-type Plasminogen Activator (uPA) Binding to the uPA Receptor (uPAR) Promotes Axonal Regeneration in the Central Nervous System." in: The Journal of biological chemistry, Vol. 292, Issue 7, pp. 2741-2753, (2017) (PubMed).

Göbel, Pankratz, Asaridou, Herrmann, Bittner, Merker, Ruck, Glumm, Langhauser, Kraft, Krug, Breuer, Herold, Gross, Beckmann, Korb-Pap, Schuhmann, Kuerten, Mitroulis, Ruppert, Nolte, Panousis, Klotz et al.: "Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. ..." in: Nature communications, Vol. 7, pp. 11626, (2016) (PubMed).

Magnussen, Hadler-Olsen, Latysheva, Pirila, Steigen, Hanes, Salo, Winberg, Uhlin-Hansen, Svineng: "Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes." in: PLoS ONE, Vol. 9, Issue 8, pp. e105929, (2015) (PubMed).

Spinale, Mariani, Kapoor, Zhang, Weyant, Song, Wong, Troost, Gadegbeku, Gipson, Kretzler, Nihalani, Holzman: "A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease." in: Kidney international, Vol. 87, Issue 3, pp. 564-74, (2015) (PubMed).

Yang, Duh, Caldwell, Behzadian: "Antipermeability function of PEDF involves blockade of the MAP kinase/GSK/beta-catenin signaling pathway and uPAR expression." in: Investigative ophthalmology & visual science, Vol. 51, Issue 6, pp. 3273-80, (2010) (PubMed).

Viswanathan, Richardson, Togonu-Bickersteth, Dai, Liu, Vatsya, Sun, Yu, Munuswamy-Ramanujam, Baker, Lucas: "Myxoma viral serpin, Serp-1, inhibits human monocyte adhesion through regulation of actin-binding protein filamin B." in: Journal of leukocyte biology, Vol. 85, Issue 3, pp. 418-26, (2009) (PubMed).

van Zoelen, Florquin, de Beer, Pater, Verstege, Meijers, van der Poll: "Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury." in: The American journal of pathology, Vol. 174, Issue 6, pp. 2182-9, (2009) (PubMed).

Aliases for PLAUR 抗体

plasminogen activator, urokinase receptor (Plaur) 抗体
plasminogen activator, urokinase receptor (PLAUR) 抗体
Cd87 抗体
CD87 抗体
Par 抗体
PLAUR 抗体
Plaur3 抗体
u-PAR 抗体
U-PAR 抗体
uPAR 抗体
UPAR 抗体
uPAR-2 抗体
uPAR-3 抗体
URKR 抗体
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