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PKD2 产品

(Protein Kinase D2 (PKD2))

Categories

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured PKD2 Categories

PKD2 抗体

High quality antibodies with extensive validation data.

PKD2 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PKD2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PKD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), IF, IP, ICC
Validations
  • (6)
Cat. No. ABIN2855325
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN565195
Quantity 50 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, IF, FACS
Validations
  • (4)
Cat. No. ABIN1500413
Quantity 100 μL
Datasheet Datasheet

Recommended PKD2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116794
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116795
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1116796
Quantity 96 tests
Datasheet Datasheet

Recommended PKD2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316286
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316288
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317066
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PKD2 Products

Zheng, Qian, Varghese, Baker, Fuchs: "Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2." in: Molecular and cellular biology, Vol. 31, Issue 4, pp. 710-20, (2011) (PubMed).

Azoitei, Kleger, Schoo, Thal, Brunner, Pusapati, Filatova, Genze, Möller, Acker, Kuefer, Van Lint, Baust, Adler, Seufferlein: "Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation." in: Neuro-oncology, Vol. 13, Issue 7, pp. 710-24, (2011) (PubMed).

Zheng, Qian, Baker, Fuchs: "Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor." in: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35733-41, (2011) (PubMed).

Pusapati, Krndija, Armacki, von Wichert, von Blume, Malhotra, Adler, Seufferlein: "Role of the second cysteine-rich domain and Pro275 in protein kinase D2 interaction with ADP-ribosylation factor 1, trans-Golgi network recruitment, and protein transport." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1011-22, (2010) (PubMed).

Liu, Evans, Britton, Zachary: "The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis." in: Oncogene, Vol. 27, Issue 21, pp. 2989-98, (2008) (PubMed).

Sharlow, Giridhar, LaValle, Chen, Leimgruber, Barrett, Bravo-Altamirano, Wipf, Lazo, Wang: "Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone." in: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33516-26, (2008) (PubMed).

Yuan, Lugea, Zheng, Gukovsky, Edderkaoui, Rozengurt, Pandol: "Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 295, Issue 6, pp. G1190-201, (2008) (PubMed).

Bossard, Bresson, Polishchuk, Malhotra: "Dimeric PKD regulates membrane fission to form transport carriers at the TGN." in: The Journal of cell biology, Vol. 179, Issue 6, pp. 1123-31, (2007) (PubMed).

Yeaman, Ayala, Wright, Bard, Bossard, Ang, Maeda, Seufferlein, Mellman, Nelson, Malhotra: "Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network." in: Nature cell biology, Vol. 6, Issue 2, pp. 106-12, (2004) (PubMed).

Rey, Yuan, Rozengurt: "Intracellular redistribution of protein kinase D2 in response to G-protein-coupled receptor agonists." in: Biochemical and biophysical research communications, Vol. 302, Issue 4, pp. 817-24, (2003) (PubMed).

Synonyms and alternative names related to PKD2

protein kinase D2 (PRKD2), protein kinase D2 (Prkd2), serine/threonine-protein kinase D2 (LOC100407181), AI325941, nPKC-D2, PKD2, PRKD2, RGD1308054

Protein level used designations for PKD2

  • serine/threonine-protein kinase D2
  • nPKC-D2
  • protein kinase D2
  • serine/threonine-protein kinase D2-like
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