PKC beta 产品
(Protein Kinase C, beta (PRKCB))
Categories
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Featured PKC beta Categories
PKC beta 抗体
High quality antibodies with extensive validation data.
PKC beta ELISA试剂盒
Reliable ELISA kits for a wide range of species.
PKC beta 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PKC beta 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6146199
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (4)
Cat. No.
ABIN6146200
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN741240
Quantity
100 μL
Datasheet
Datasheet
Recommended PKC beta ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380789
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended PKC beta 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316257
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2729604
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2729603
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our PKC beta Products
: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).: "Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding." in: Molecular and cellular biology, Vol. 38, Issue 19, (2018) (PubMed).
: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." in: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).
: "Different localization and expression of protein kinase C-beta in kidney cortex of diabetic nephropathy mice and its role in telmisartan treatment." in: American journal of translational research, Vol. 7, Issue 6, pp. 1116-25, (2015) (PubMed).
: "PKC? suppresses osteoblastic differentiation." in: Bone, Vol. 48, Issue 3, pp. 476-84, (2011) (PubMed).
: "Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 185-92, (2010) (PubMed).
: "trans-resveratrol inhibits hyperglycemia-induced inflammation and connexin downregulation in retinal pigment epithelial cells." in: Journal of agricultural and food chemistry, Vol. 58, Issue 14, pp. 8246-52, (2010) (PubMed).
: "Small-molecule synergist of the Wnt/beta-catenin signaling pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 18, pp. 7444-8, (2007) (PubMed).
: "Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 25, Issue 13, pp. 1741-6, (2007) (PubMed).
: "Human biliverdin reductase, a previously unknown activator of protein kinase C betaII." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8110-22, (2007) (PubMed).
Synonyms and alternative names related to PKC beta
protein kinase C beta (PRKCB), protein kinase C, beta (Prkcb), protein kinase C, beta b (prkcbb), protein kinase C, beta a (prkcba), A130082F03Rik, PKC, PKC-B, PKC-beta, PKC-Beta, Pkc53E, PKCB, Pkcb, Prkcb, PRKCB1, Prkcb1, prkcb1, prkcb1l, PRKCB2, Prkcb2, PRKCB_tv2, zgc:63591, zgc:64063Protein level used designations for PKC beta
- PKC-B
- protein kinase C beta type
- protein kinase C, beta 1 polypeptide
- protein kinase C beta-II
- protein kinase C, beta 1
- PKC-beta
- protein kinase C beta I
- protein kinase C beta II
- protein kinase C beta 1
- protein kinase C, beta
- protein kinase C beta 2
- protein kinase C, beta 1, like
- protein kinase C, beta a
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