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PINX1 产品

(PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor (By similarity).

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Featured PINX1 Categories

PINX1 抗体

High quality antibodies with extensive validation data.

PINX1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PINX1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PINX1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
  • (2)
Cat. No. ABIN565796
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6264227
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IHC (p)
Validations
  • (1)
Cat. No. ABIN1387106
Quantity 100 μL
Datasheet Datasheet

Recommended PINX1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1148151
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1148152
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1148153
Quantity 96 tests
Datasheet Datasheet

Recommended PINX1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124453
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN666767
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315118
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PINX1 Products

Hou, Li, Yong, Chen, Chu, Zheng, Bai: "PinX1 represses renal cancer angiogenesis via the mir-125a-3p/VEGF signaling pathway." in: Angiogenesis, (2019) (PubMed).

Uziel, Yosef, Sharan, Ruppin, Kupiec, Kushnir, Beery, Cohen-Diker, Nordenberg, Lahav: "The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis." in: Genomics, Vol. 105, Issue 1, pp. 5-16, (2014) (PubMed).

Wang, Yu, Yuan, Lan, Jin, Huang: "Plk1-mediated mitotic phosphorylation of PinX1 regulates its stability." in: European journal of cell biology, Vol. 89, Issue 10, pp. 748-56, (2010) (PubMed).

Ma, Wu, Liu, Xu, Li, Li: "The correlation of genetic instability of PINX1 gene to clinico-pathological features of gastric cancer in the Chinese population." in: Journal of cancer research and clinical oncology, Vol. 135, Issue 3, pp. 431-7, (2009) (PubMed).

Li, Yuan, Yan, Huo, Zhu, Liu, Guo, Yao: "PinX1 is recruited to the mitotic chromosome periphery by Nucleolin and facilitates chromosome congression." in: Biochemical and biophysical research communications, Vol. 384, Issue 1, pp. 76-81, (2009) (PubMed).

Banik, Counter: "Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 51745-8, (2004) (PubMed).

Zhou, Lu: "The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor." in: Cell, Vol. 107, Issue 3, pp. 347-59, (2001) (PubMed).

Synonyms and alternative names related to PINX1

PIN2/TERF1 interacting telomerase inhibitor 1 (PINX1), PIN2/TERF1 interacting, telomerase inhibitor 1 (PINX1), PIN2/TERF1 interacting, telomerase inhibitor 1 (Pinx1), 67-11-3, 2210403I16Rik, 2610028A01Rik, AU024023, LPTL, LPTS, LPTS1, PINX1, RGD1566025

Protein level used designations for PINX1

  • PIN2-interacting protein 1
  • 67-11-3 protein
  • PIN2 interacting protein 1
  • PIN2/TERF1-interacting telomerase inhibitor 1
  • TRF1-interacting protein 1
  • hepatocellular carcinoma-related putative tumor suppressor
  • liver-related putative tumor suppressor
  • pin2-interacting protein X1
  • protein 67-11-3
  • PIN2-interacting protein X1
  • PIN2/TRF1-interacting protein
  • Pin2-interacting protein X1
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