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PIM1 产品

(Pim-1 Oncogene (PIM1))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured PIM1 Categories

PIM1 抗体

High quality antibodies with extensive validation data.

PIM1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PIM1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIM1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7429160
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
Cat. No. ABIN562235
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6264220
Quantity 100 μL
Datasheet Datasheet

Recommended PIM1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958588
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1503732
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1503733
Quantity 96 tests
Datasheet Datasheet

Recommended PIM1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124452
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315100
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315102
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PIM1 Products

Xu, Xiong, Cao, Huang, Wang, You, Zhou, Zheng, Hu, Zhang, Zhao: "PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." in: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).

Albertson, Schmidt, Bearss, Tripp, Bearss, Liu: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).

Wu, Lu, He, Jin: "PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population." in: OncoTargets and therapy, Vol. 9, pp. 2919-25, (2016) (PubMed).

Plum, Warnecke-Eberz, Dhaouadi, Alakus, Drebber, Metzger, Prenzel, Hölscher, Bollschweiler: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).

Herzog, Fink, Weitmann, Friedel, Hadlich, Langner, Kindermann, Holm, Böhm, Eskilsson, Miletic, Hildner, Fritsch, Vogelgesang, Havemann, Ritter, Meyer zu Schwabedissen, Rauch, Hoffmann, Kroemer et al.: "Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. ..." in: Neuro-oncology, Vol. 17, Issue 2, pp. 223-42, (2015) (PubMed).

Egli, Zajonz, Burger, Schweighoffer: "Human CD180 Transmits Signals via the PIM-1L Kinase." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142741, (2015) (PubMed).

Menter, Ernst, Drachneris, Dirnhofer, Barghorn, Went, Tzankov: "Phenotype profiling of primary testicular diffuse large B-cell lymphomas." in: Hematological oncology, Vol. 32, Issue 2, pp. 72-81, (2014) (PubMed).

Renard, Paulin, Breuils-Bonnet, Simard, Pibarot, Bonnet, Provencher: "Pim-1: A new biomarker in pulmonary arterial hypertension." in: Pulmonary circulation, Vol. 3, Issue 1, pp. 74-81, (2013) (PubMed).

Ha, Iqbal, Mita, Ruoff, Gerald, Lepor, Taneja, Lee, Melamed, Garabedian, Logan: "Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer." in: Oncogene, Vol. 32, Issue 34, pp. 3992-4000, (2013) (PubMed).

Baron, Anastasi, Hyjek, Bies, Reddy, Dong, Joseph, Thirman, Wroblewski, Wolff, Baron: "PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5735-9, (2012) (PubMed).

Synonyms and alternative names related to PIM1

Pim-1 proto-oncogene, serine/threonine kinase (PIM1), proviral integration site 1 (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (pim1), Pim-1 proto-oncogene, serine/threonine kinase L homeolog (pim1.L), PIM, pim, Pim-1, pim-1, PIM1, pim3

Protein level used designations for PIM1

  • Oncogene PIM1
  • pim-1 kinase 44 kDa isoform
  • pim-1 oncogene (proviral integration site 1)
  • proto-oncogene serine/threonine-protein kinase pim-1
  • serine/threonine-protein kinase pim-1
  • pim-1 oncogene
  • non-specific serine/threonine protein kinase
  • proto-oncogene serine/threonine-protein kinase Pim-1
  • proviral integration site 1
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