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PIKFYVE 蛋白

(phosphoinositide Kinase, FYVE Finger Containing (PIKFYVE))
Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve\; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD)\; an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010].
PIKFYVE Protein (AA 1-451) (GST tag) PIKFYVE Protein (AA 1-451) (GST tag) PIKFYVE Protein (AA 1-451) (GST tag) (ABIN1315147)

PIKFYVE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

PIKFYVE Protein (AA 342-451) (GST tag) PIKFYVE Protein (AA 342-451) (GST tag) PIKFYVE Protein (AA 342-451) (GST tag) (ABIN1315149)

PIKFYVE 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

PIKFYVE Protein (AA 1680-1931) (His tag) (ABIN7405229)

PIKFYVE 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, Imm, PC

PIKFYVE 蛋白 by Origin

Find PIKFYVE 蛋白 for a variety of species such as anti-Human PIKFYVE, anti-Mouse PIKFYVE. The species listed below are among those available. Click on a link to go to the corresponding products.

PIKFYVE 蛋白 by Source

Here you will find PIKFYVE 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PIKFYVE 蛋白 by 蛋白类型

Here you can find PIKFYVE 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

PIKFYVE 蛋白 by 应用范围

Find PIKFYVE 蛋白 validated for a specific application such as WB, AbP, ELISA, STD. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PIKFYVE 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315147
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315149
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405229
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2729013
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3011153
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729011
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2729012
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
Cat. No. ABIN6700371
Quantity 50 μg
Datasheet Datasheet

Aliases for PIKFYVE 蛋白

phosphoinositide kinase, FYVE finger containing (pikfyve) 蛋白
phosphoinositide kinase, FYVE-type zinc finger containing (PIKFYVE) 蛋白
phosphoinositide kinase, FYVE type zinc finger containing (Pikfyve) 蛋白
phosphoinositide kinase, FYVE-type zinc finger containing (Pikfyve) 蛋白
5230400C17Rik 蛋白
CFD 蛋白
FAB1 蛋白
fab1-like 蛋白
p235 蛋白
PIP5K 蛋白
Pip5k 蛋白
pip5k3 蛋白
PIP5K3 蛋白
Pip5k3 蛋白
Pipk5k3 蛋白
PipkIII 蛋白
wu:fo93c03 蛋白
ZFYVE29 蛋白
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