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PIK3R2 产品

(Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

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Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2012].

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Featured PIK3R2 Categories

PIK3R2 抗体

High quality antibodies with extensive validation data.

PIK3R2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIK3R2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (4)
Cat. No. ABIN7189409
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7101736
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7163167
Quantity 100 μg
Datasheet Datasheet

Recommended PIK3R2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3094315
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3131339
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
Cat. No. ABIN6700377
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PIK3R2 Products

Jung, Jung, Yim, Jung, Choi, Kang, Park, Oh, Kim, Lee, Chung: "Predictive microRNAs for lymph node metastasis in endoscopically resectable submucosal colorectal cancer." in: Oncotarget, Vol. 7, Issue 22, pp. 32902-15, (2016) (PubMed).

Brehme, Hantschel, Colinge, Kaupe, Planyavsky, Köcher, Mechtler, Bennett, Superti-Furga: "Charting the molecular network of the drug target Bcr-Abl." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 18, pp. 7414-9, (2009) (PubMed).

Hale, Batty, Downes, Randall: "Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation." in: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1372-80, (2008) (PubMed).

Ehrhardt, Wolff, Pleschka, Planz, Beermann, Bode, Schmolke, Ludwig: "Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses." in: Journal of virology, Vol. 81, Issue 7, pp. 3058-67, (2007) (PubMed).

Khan, Di Cello, Nath, Kim: "Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells." in: Journal of neurovirology, Vol. 9, Issue 6, pp. 584-93, (2003) (PubMed).

Deregibus, Cantaluppi, Doublier, Brizzi, Deambrosis, Albini, Camussi: "HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells." in: The Journal of biological chemistry, Vol. 277, Issue 28, pp. 25195-202, (2002) (PubMed).

Cook, August, Henderson: "Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 1, pp. 254-60, (2002) (PubMed).

Synonyms and alternative names related to PIK3R2

phosphoinositide-3-kinase regulatory subunit 2 (PIK3R2), phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta) (pik3r2), phosphoinositide-3-kinase regulatory subunit 2 (Pik3r2), phosphoinositide-3-kinase, regulatory subunit 2 (beta) (pik3r2), MGC80449, MPPH, p85, p85-BETA, P85B, p85beta, pik3r2

Protein level used designations for PIK3R2

  • PI3-kinase subunit p85-beta
  • PI3K regulatory subunit beta
  • phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta
  • phosphatidylinositol 3-kinase regulatory subunit beta
  • phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
  • ptdIns-3-kinase regulatory subunit p85-beta
  • PI3-kinase p85 subunit beta
  • PI3-kinase regulatory subunit beta
  • phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)
  • phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
  • ptdIns-3-kinase p85-beta
  • ptdIns-3-kinase regulatory subunit beta
  • phosphatidylinositol 3-kinase regulartory subunit polypeptide 2
  • phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2
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