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PIK3CA 产品

(Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008].

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Featured PIK3CA Categories

PIK3CA 抗体

High quality antibodies with extensive validation data.

PIK3CA ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PIK3CA 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIK3CA 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
  • (6)
Cat. No. ABIN3020829
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF/ICC
Validations
  • (7)
Cat. No. ABIN1844691
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Human, Mouse, Rabbit, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN677198
Quantity 100 μL
Datasheet Datasheet

Recommended PIK3CA ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969285
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969286
Quantity 96 tests
Datasheet Datasheet
Reactivity Cow
Analytical Method
Validations
Cat. No. ABIN1147857
Quantity 96 tests
Datasheet Datasheet

Recommended PIK3CA 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315072
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7504937
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7424767
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PIK3CA Products

Song, Ju, Xiao, Wang, Liu, Fu, Liu, Gu, Li, Cheng: "Application of multifunctional targeting epirubicin liposomes in the treatment of non-small-cell lung cancer." in: International journal of nanomedicine, Vol. 12, pp. 7433-7451, (2018) (PubMed).

Dinesh, Rasool et al.: "Berberine inhibits IL-21/IL-21R mediated inflammatory proliferation of fibroblast-like synoviocytes through the attenuation of PI3K/Akt signaling pathway and ameliorates IL-21 mediated ..." in: Cytokine, Vol. 106, pp. 54-66, (2018) (PubMed).

Zhang, Chen, Tao, Kang, Xiong, Zeng, Liu, Jiang, Chen: "miR-25-3p, Positively Regulated by Transcription Factor AP-2α, Regulates the Metabolism of C2C12 Cells by Targeting Akt1." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).

Li, Lu, Bai, Xiao, Guo, Dong: "Ginsenoside Rg3 Suppresses Proliferation and Induces Apoptosis in Human Osteosarcoma." in: BioMed research international, Vol. 2018, pp. 4306579, (2018) (PubMed).

Shin, Choi, Kim, Yu, Shin, Choi, Roh: "High doses of caffeine reduce in vivo osteogenic activity in prepubertal rats." in: Journal of anatomy, Vol. 227, Issue 1, pp. 10-20, (2015) (PubMed).

Lou, Villagran, Boland, Im, Polo, Zhou, Odey, Juárez-Torres, Medina-Martínez, Roman-Basaure, Mitchell, Roberson, Sawitzke, Garland, Rodríguez-Herrera, Wells, Troyer, Pinto, Bass, Zhang, Castillo et al.: "Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway. ..." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 21, Issue 23, pp. 5360-70, (2015) (PubMed).

Paul-Samojedny, Suchanek, Borkowska, Pude?ko, Owczarek, Kowalczyk, Machnik, Fila-Dani?ow, Kowalski: "Knockdown of AKT3 (PKB?) and PI3KCA suppresses cell viability and proliferation and induces the apoptosis of glioblastoma multiforme T98G cells." in: BioMed research international, Vol. 2014, pp. 768181, (2014) (PubMed).

Wang, Sun, Li, Dong, Li, Zhao: "Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 151-8, (2014) (PubMed).

Redondo-Muñoz, Rodríguez, Silió, Pérez-García, Valpuesta, Carrera: "Phosphoinositide 3-kinase beta controls replication factor C assembly and function." in: Nucleic acids research, Vol. 41, Issue 2, pp. 855-68, (2013) (PubMed).

Won, Jung, Chun, Kang, Kim, Sun, Kim: "Difference in expression of EGFR, pAkt, and PTEN between oropharyngeal and oral cavity squamous cell carcinoma." in: Oral oncology, Vol. 48, Issue 10, pp. 985-90, (2012) (PubMed).

Synonyms and alternative names related to PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA), Phosphoinositide-3-kinase, catalytic, alpha polypeptide (GL50803_14855), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (pik3ca), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (Pik3ca), phosphoinositide-3-kinase regulatory subunit 1 (Pik3r1), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (Pik3ca), 6330412C24Rik, AA414921, C-P3K, C530050K14, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, p50alpha, p55alpha, p85alpha, p110, p110-alpha, p110alpha, pi3-k, PI3-kinase, PI3K, pi3k, PI3K-alpha

Protein level used designations for PIK3CA

  • PI3-kinase p110 subunit alpha
  • PI3K-alpha
  • phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha
  • phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
  • phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • ptdIns-3-kinase subunit p110-alpha
  • serine/threonine protein kinase PIK3CA
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • phosphoinositide 3-kinase catalytic subunit
  • Phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • PI3-kinase subunit alpha
  • PI3K
  • PI3Kalpha
  • p110alpha
  • phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha
  • phosphoinositide-3-kinase catalytic alpha polypeptide
  • ptdIns-3-kinase p110
  • ptdIns-3-kinase subunit alpha
  • PI3-kinase regulatory subunit alpha
  • PI3-kinase subunit p85-alpha
  • PI3K regulatory subunit alpha
  • phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
  • phosphatidylinositol 3-kinase regulatory subunit alpha
  • ptdIns-3-kinase regulatory subunit alpha
  • ptdIns-3-kinase regulatory subunit p85-alpha
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