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PIGP 产品

(Phosphatidylinositol Glycan Anchor Biosynthesis, Class P (PIGP))

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This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Featured PIGP Categories

PIGP 抗体

High quality antibodies with extensive validation data.

PIGP 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIGP 抗体

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Reactivity
Application
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Cat. No.
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Datasheet
Reactivity Human, Mouse
Application ELISA, WB, IHC
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  • (3)
Cat. No. ABIN6264206
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
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  • (2)
Cat. No. ABIN7163218
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN565565
Quantity 100 μg
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Recommended PIGP ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6216337
Quantity 96 tests
Datasheet Datasheet

Recommended PIGP 蛋白

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Reactivity
Source
Validations
Cat. No.
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Datasheet
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Source Wheat germ
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Cat. No. ABIN1315031
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3098767
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3129973
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Latest Publications for our PIGP Products

Uhlén, Oksvold, Älgenäs, Hamsten, Fagerberg, Klevebring, Lundberg, Odeberg, Pontén, Kondo, Sivertsson: "Antibody-based protein profiling of the human chromosome 21." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. M111.013458, (2012) (PubMed).

Choi, Suzuki, Yoshimura, Togashi, Hida, Taylor, Wang, Sugano, Hattori, Sakaki: "Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5)." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 12, Issue 5, pp. 347-51, (2001) (PubMed).

Togashi, Choi, Taylor, Suzuki, Sugano, Hattori, Sakaki: "A novel gene, DSCR5, from the distal Down syndrome critical region on chromosome 21q22.2." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 3, pp. 207-12, (2000) (PubMed).

Watanabe, Murakami, Marmor, Inoue, Maeda, Hino, Kangawa, Julius, Kinoshita: "Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2." in: The EMBO journal, Vol. 19, Issue 16, pp. 4402-11, (2000) (PubMed).

Synonyms and alternative names related to PIGP

phosphatidylinositol glycan anchor biosynthesis class P (PIGP), phosphatidylinositol glycan anchor biosynthesis class P (pigp), phosphatidylinositol glycan anchor biosynthesis, class P (Pigp), phosphatidylinositol glycan anchor biosynthesis, class P (pigp), DCRC, dcrc, Dcrc, DCRC-S, dcrc-s, DSCR5, dscr5, Dscr5, DSRC, dsrc, PIGP, Pigp, wu:fc66d08, zgc:73366

Protein level used designations for PIGP

  • Down syndrome critical region gene 5
  • Down syndrome critical region protein 5
  • Down syndrome critical region protein C
  • PIG-P
  • phosphatidylinositol N-acetylglucosaminyltransferase subunit P
  • phosphatidylinositol glycan, class P
  • phosphatidylinositol-glycan biosynthesis class P protein
  • phosphatidylinositol-n-acetylglucosaminyltranferase subunit
  • Down syndrome critical region gene c
  • Down syndrome critical region homolog 5
  • down syndrome critical region protein 5 homolog
  • phosphatidylinositol glycan anchor biosynthesis, class P
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