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PIEZO1 产品

(Piezo-Type Mechanosensitive Ion Channel Component 1 (PIEZO1))
Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types (Coste et al., 2010 [PubMed 20813920]).[supplied by OMIM, Nov 2010].

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Featured PIEZO1 Categories

PIEZO1 抗体

High quality antibodies with extensive validation data.

PIEZO1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

PIEZO1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PIEZO1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6145612
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7163444
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6264200
Quantity 100 μL
Datasheet Datasheet

Recommended PIEZO1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969323
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969322
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6234490
Quantity 96 tests
Datasheet Datasheet

Recommended PIEZO1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353525
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2746603
Quantity 5 applications
Datasheet Datasheet

Latest Publications for our PIEZO1 Products

Mazzuoli-Weber, Kugler, Bühler, Kreutz, Demir, Ceyhan, Zeller, Schemann: "Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?" in: Cell and tissue research, Vol. 375, Issue 3, pp. 605-618, (2019) (PubMed).

Jetta, Gottlieb, Verma, Sachs, Hua: "Shear stress-induced nuclear shrinkage through activation of Piezo1 channels in epithelial cells." in: Journal of cell science, Vol. 132, Issue 11, (2019) (PubMed).

Miyazaki, Sugimoto, Yoshizaki, Kawarabayashi, Iwata, Kurogoushi, Kitamura, Otsuka, Hasegawa, Akazawa, Fukumoto, Ishimaru, Iwamoto: "Coordination of WNT signaling and ciliogenesis during odontogenesis by piezo type mechanosensitive ion channel component 1." in: Scientific reports, Vol. 9, Issue 1, pp. 14762, (2019) (PubMed).

Hope, Lopez-Cavestany, Wang, Reinhart-King, King: "Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability." in: Cell death & disease, Vol. 10, Issue 11, pp. 837, (2019) (PubMed).

Jiang, Zhao, Chen: "The Function of the Novel Mechanical Activated Ion Channel Piezo1 in the Human Osteosarcoma Cells." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 5070-5082, (2018) (PubMed).

Gudipaty, Lindblom, Loftus, Redd, Edes, Davey, Krishnegowda, Rosenblatt: "Mechanical stretch triggers rapid epithelial cell division through Piezo1." in: Nature, Vol. 543, Issue 7643, pp. 118-121, (2017) (PubMed).

Lee, Guevarra, Nguyen, Chua, Wang, Jacobs: "The primary cilium functions as a mechanical and calcium signaling nexus." in: Cilia, Vol. 4, pp. 7, (2015) (PubMed).

Li, Zhang, Chen, Cui, Zhang: "Piezo1 protein induces the apoptosis of human osteoarthritis-derived chondrocytes by activating caspase-12, the signaling marker of ER stress." in: International journal of molecular medicine, Vol. 40, Issue 3, pp. 845-853 (PubMed).

Synonyms and alternative names related to PIEZO1

piezo type mechanosensitive ion channel component 1 (PIEZO1), piezo-type mechanosensitive ion channel component 1 (Piezo1), 9630020g22, DHS, FAM38A, Fam38a, Mib, mKIAA0233

Protein level used designations for PIEZO1

  • family with sequence similarity 38, member A
  • membrane protein induced by beta-amyloid treatment
  • protein PIEZO1
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