PI3K p85a/g/b 抗体 (AA 465-469)
PI3K p85a/g/b
适用: 人, 小鼠, 大鼠
IHC
宿主: 兔
Polyclonal
unconjugated
(2 references)-
- 抗原
- PI3K p85a/g/b (Phosphoinositide 3 Kinase, p85 alpha/gamma/beta (PI3K p85a/g/b))
- 抗原表位
- AA 465-469
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Immunohistochemistry (IHC)
- 特异性
- The antibody detects endogenous level of total PI3K P85 a/g/b protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
- 免疫原
- Peptide sequence around AA 465-469, 197-201, 462-466 (L-Y-E-E-Y) derived from Human PI3K P85. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- 亚型
- IgG
-
- 应用备注
- Immunohistochemistry: 1:50-1:100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
: "Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells." in: Lipids in health and disease, Vol. 12, pp. 83, (2013) (PubMed).
: "The "HER2-PI3K/Akt-FASN Axis" regulated malignant phenotype of colorectal cancer cells." in: Lipids, Vol. 47, Issue 4, pp. 403-11, (2012) (PubMed).
-
: "Loss of fatty acid synthase inhibits the "HER2-PI3K/Akt axis" activity and malignant phenotype of Caco-2 cells." in: Lipids in health and disease, Vol. 12, pp. 83, (2013) (PubMed).
-
- 抗原
- PI3K p85a/g/b (Phosphoinositide 3 Kinase, p85 alpha/gamma/beta (PI3K p85a/g/b))
- 别名
- PI3K P85 alpha/gamma/beta
- 背景
- PI3K binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
- 分子量
- 85 kDa
- UniProt
- O00459
-
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