Phospholipase C gamma 2 产品
(Phospholipase C gamma 2 (PLCG2))
Categories
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. [provided by RefSeq, Sep 2011].
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Featured Phospholipase C gamma 2 Categories
Phospholipase C gamma 2 抗体
High quality antibodies with extensive validation data.
Phospholipase C gamma 2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Phospholipase C gamma 2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Phospholipase C gamma 2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN3023145
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (4)
Cat. No.
ABIN518951
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (4)
Cat. No.
ABIN948268
Quantity
100 μL
Datasheet
Datasheet
Recommended Phospholipase C gamma 2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969306
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958573
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380130
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended Phospholipase C gamma 2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397702
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094665
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136487
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Phospholipase C gamma 2 Products
: "PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras." in: Science signaling, Vol. 6, Issue 304, pp. ra105, (2013) (PubMed).: "Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells." in: Molecular immunology, Vol. 46, Issue 15, pp. 3029-36, (2009) (PubMed).
: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, (2004) (PubMed).
: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, (2004) (PubMed).
: "Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker." in: The Journal of biological chemistry, Vol. 279, Issue 36, pp. 37651-61, (2004) (PubMed).
: "Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 38595-601, (2001) (PubMed).
: "Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C." in: The Journal of biological chemistry, Vol. 275, Issue 39, pp. 30220-5, (2000) (PubMed).
: "Complete cDNA encoding a putative phospholipase C from transformed human lymphocytes." in: FEBS letters, Vol. 242, Issue 1, pp. 31-5, (1989) (PubMed).
Synonyms and alternative names related to Phospholipase C gamma 2
phospholipase C, gamma 2 (Plcg2), phospholipase C gamma 2 (PLCG2), phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2), phospholipase C gamma 2 (Plcg2), APLAID, FCAS3, Plcg-2, PLCgamma2Protein level used designations for Phospholipase C gamma 2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2
- PLC-gamma-2
- phosphoinositide phospholipase C-gamma-2
- phospholipase C-gamma-2
- PLC-IV
- phosphoinositide phospholipase C
- phospholipase C-IV
- phosphatidylinositol-specific phospholipase C
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