Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 产品
(Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
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This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].
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Featured Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Categories
Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 抗体
High quality antibodies with extensive validation data.
Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p), IF
Validations
- (6)
Cat. No.
ABIN1500202
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, IHC, IHC (p), IF
Validations
- (7)
Cat. No.
ABIN1500203
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (10)
Cat. No.
ABIN1500207
Quantity
100 μL
Datasheet
Datasheet
Recommended Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2728968
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094659
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3137255
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Products
: "The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma." in: Molecular cancer, Vol. 17, Issue 1, pp. 93, (2018) (PubMed).: "Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLC? and to Activate p44/42 MAPK in Human Aortic Endothelial ..." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132835, (2015) (PubMed).
: "Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin ..." in: Endocrinology, Vol. 145, Issue 6, pp. 2845-57, (2004) (PubMed).
: "The IL-1 receptor accessory protein is essential for PI 3-kinase recruitment and activation." in: Biochemical and biophysical research communications, Vol. 316, Issue 4, pp. 1022-8, (2004) (PubMed).
: "Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells." in: Oncogene, Vol. 22, Issue 3, pp. 392-400, (2003) (PubMed).
: "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." in: Journal of virology, Vol. 77, Issue 4, pp. 2539-49, (2003) (PubMed).
: "Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation." in: Molecular pharmacology, Vol. 63, Issue 3, pp. 639-45, (2003) (PubMed).
: "Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45." in: Journal of cancer research and clinical oncology, Vol. 130, Issue 1, pp. 8-14, (2003) (PubMed).
Synonyms and alternative names related to Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (Pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (Pik3cg), si:rp71-17i16.5 (si:rp71-17i16.5), 5830428L06Rik, p110gamma, p120-PI3K, PI3CG, PI3K, Pi3k, pi3k, PI3Kgamma, PIK3, wu:fb15d07, zgc:77033Protein level used designations for Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide
- 1-phosphatidylinositol 3-kinase
- PI3-kinase subunit gamma
- PI3K-gamma
- p110-gamma
- p110gamma
- p120-PI3K
- phosphatidylinositol 3 kinase gamma, p110 gamma
- phosphatidylinositol 3-kinase catalytic 110-kD gamma
- phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
- phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
- phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
- phosphoinositide-3-kinase gamma catalytic subunit
- phosphoinositide-3-kinase, catalytic, gamma polypeptide
- ptdIns-3-kinase subunit gamma
- ptdIns-3-kinase subunit p110-gamma
- serine/threonine protein kinase PIK3CG
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like
- PI3Kgamma
- catalytic subunit of G-beta-gamma-activated
- phosphoinositide-3-kinase catalytic gamma polypeptide
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