PHLPP1 抗体
(PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))
This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011].
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PHLPP1 抗体 by 适用
Find PHLPP1 抗体 for a variety of species such as anti-Human PHLPP1, anti-Mouse PHLPP1, anti-Rat PHLPP1. The species listed below are among those available. Click on a link to go to the corresponding products.
PHLPP1 抗体 by 应用范围
Find PHLPP1 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
PHLPP1 抗体 by 抗体来源
Find PHLPP1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
PHLPP1 抗体 by 抗原表位
Find PHLPP1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
PHLPP1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal PHLPP1 抗体. Click on a link to go to the corresponding products.
PHLPP1 抗体 by 克隆
Find PHLPP1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
PHLPP1 抗体 by 标记
Find PHLPP1 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular PHLPP1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN6145573
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7130610
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6264947
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN1804212
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (1)
Cat. No.
ABIN7264821
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, IP
Validations
Cat. No.
ABIN7117369
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
Cat. No.
ABIN2764065
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
Cat. No.
ABIN6991746
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN1840456
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA
Validations
Cat. No.
ABIN2884713
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN5620520
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ICC
Validations
Cat. No.
ABIN603650
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN392310
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, EIA
Validations
- (1)
Cat. No.
ABIN1449987
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, EIA
Validations
- (1)
Cat. No.
ABIN360194
Quantity
0.4 mL
Datasheet
Datasheet
Latest Publications for our PHLPP1 抗体
: "RNA-binding Protein Trinucleotide repeat-containing 6A Regulates the Formation of Circular RNA 0006916, with Important Functions in Lung Cancer Cells." in: Carcinogenesis, (2018) (PubMed).: "Interactome of the negative regulator of nuclear import BRCA1-binding protein 2." in: Scientific reports, Vol. 5, pp. 9459, (2015) (PubMed).
: "Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1." in: Science signaling, Vol. 6, Issue 267, pp. ra19, (2013) (PubMed).
: "mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells." in: The Journal of biological chemistry, Vol. 286, Issue 8, pp. 6510-20, (2011) (PubMed).
: "Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein ..." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19777-88, (2011) (PubMed).
: "Cell-type-specific regulation of raft-associated Akt signaling." in: Cell death & disease, Vol. 2, pp. e145, (2011) (PubMed).
: "IGF-I activation of the AKT pathway is impaired in visceral but not subcutaneous preadipocytes from obese subjects." in: Endocrinology, Vol. 151, Issue 8, pp. 3752-63, (2010) (PubMed).
: "Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN ..." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 27900-10, (2010) (PubMed).
: "Depletion of Pleckstrin homology domain leucine-rich repeat protein phosphatases 1 and 2 by Bcr-Abl promotes chronic myelogenous leukemia cell proliferation through continuous phosphorylation of Akt ..." in: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22155-65, (2009) (PubMed).
: "Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C." in: The Journal of biological chemistry, Vol. 284, Issue 22, pp. 15215-23, (2009) (PubMed).
Aliases for PHLPP1 抗体
PH domain and leucine rich repeat protein phosphatase 1 (PHLPP1) 抗体PH domain and leucine rich repeat protein phosphatase 1 (phlpp1) 抗体
PH domain and leucine rich repeat protein phosphatase 1 (Phlpp1) 抗体
AI836256 抗体
mKIAA0606 抗体
PHLPP 抗体
Phlpp 抗体
PLEKHE1 抗体
Plekhe1 抗体
SCOP 抗体
Scop 抗体
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