PHC1 产品
(Polyhomeotic-Like 1 (PHC1))
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This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008].
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PHC1 抗体
High quality antibodies with extensive validation data.
Recommended PHC1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (1)
- (4)
Cat. No.
ABIN1724838
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (1)
- (3)
Cat. No.
ABIN515164
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN515166
Quantity
100 μg
Datasheet
Datasheet
Recommended PHC1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3094531
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PHC1 Products
: "Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis." in: Human molecular genetics, Vol. 22, Issue 11, pp. 2200-13, (2013) (PubMed).: "Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program." in: The Journal of biological chemistry, Vol. 288, Issue 9, pp. 6238-47, (2013) (PubMed).
: "Polycomb complexes repress developmental regulators in murine embryonic stem cells." in: Nature, Vol. 441, Issue 7091, pp. 349-53, (2006) (PubMed).
: "Dissociation of mammalian Polycomb-group proteins, Ring1B and Rae28/Ph1, from the chromatin correlates with configuration changes of the chromatin in mitotic and meiotic prophase." in: Histochemistry and cell biology, Vol. 120, Issue 2, pp. 111-9, (2003) (PubMed).
Synonyms and alternative names related to PHC1
polyhomeotic homolog 1 (Phc1), polyhomeotic homolog 1 (PHC1), polyhomeotic-like 1 (Drosophila) (Phc1), AW557034, Edr, EDR1, Edr1, HPH1, Mph1, Rae-28, RAE28, rae28Protein level used designations for PHC1
- polyhomeotic-like 1
- polyhomeotic-like protein 1
- early development regulator 1 (homolog of polyhomeotic 1)
- early development regulatory protein 1
- early development regulator1 (homolog of polyhomeotic 1)
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